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US4075350A Expired / Lapsed US ⏱️ 0.0 years remaining

Antimicrobial compositions employing certain betaines and certain amine oxides

Assignee: Biosyn Inc
•
Filing: 1975-12-18
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Granted: 1978-02-21
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Expires: 1995-12-18
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Abstract

Abstract There is provided an antimicrobial composition of low toxicity having enhanced gram positive and gram negative activity and comprises: (a) an acyl-N-betaine (0.1 part - 40.0 parts, by weight), (b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide (0.1 part - 40.0 parts, by weight), and (c) a protonating agent, such as hydrochloric acid, acetic acid or citric acid in an amount sufficient to adjust the pH of the overall composition to about 5.5 or below. The composition exhibits deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.

Inventors

  • 👤 Edwin B. Michaels

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 12:43
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A01; A01N; A01N33/00; A01N33/16; A01N33/24; A01N37/00; A01N37/18; A01N37/20; A01N37/44; A01N37/46; A01N41/00; A01N41/02; A01N41/04; A61K31/00; A61K31/185; A61K31/205; A61K8/44; A61Q; A61Q15/00; A61Q17/00; A61Q17/005; A61Q19/00; A61Q19/10; A61Q5/00; A61Q5/02; C; C11; C11D; C11D1/00; C11D1/66; C11D1/75; C11D1/88; C11D1/94; C11D3/00; C11D3/0005; C11D3/0068; C11D3/48

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 107 words
A broad spectrum antimicrobial composition having low toxicity which consists essentially of: (a) 0.1 to 40 parts, by weight, of a higher acyl-N-betaine said betaine having the structure: ##STR3## where R is a higher alkyl of from 10 to 18 carbon atoms, (b) 0.1 to 40 parts, by weight, of (1) a higher alkyl-N,N-dimethylamine oxide, (2) a higher alkyl-N,N-dihydroxyethylamine oxide, or (3) an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl of from 10 to 18 carbon atoms, or mixtures of the same, and (c) a protonating agent, sufficient to adjust the pH of said composition from 4 to 5.5.
Claim 2
Dependent Claim 107 words
A broad spectrum antimicrobial composition having low toxicity which consists essentially of: (a) 0.1 to 40 parts, by weight, of a higher acyl-N-betaine said betaine having the structure: ##STR3## where R is a higher alkyl of from 10 to 18 carbon atoms, (b) 0.1 to 40 parts, by weight, of (1) a higher alkyl-N,N-dimethylamine oxide, (2) a higher alkyl-N,N-dihydroxyethylamine oxide, or (3) an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl of from 10 to 18 carbon atoms, or mixtures of the same, and (c) a protonating agent, sufficient to adjust the pH of said composition from 4 to 5.5.
Claim 3
Dependent Claim 11 words
The composition according to claim 1 wherein the alkyl-N-betaine is cocoamido-N-betaine.
Claim 4
Dependent Claim 11 words
The composition according to claim 1 wherein the alkyl-N-betaine is stearylamido-N-betaine.
Claim 5
Dependent Claim 14 words
The composition according to claim 1 wherein the higher alkylamine oxide is coco-N,N-dimethylamine oxide.
Claim 6
Dependent Claim 13 words
The composition according to claim 1 wherein the protonating agent is citric acid.
Claim 7
Dependent Claim 13 words
The composition according to claim 1 wherein the protonating agent is acetic acid.
Claim 8
Dependent Claim 33 words
The composition according to claim 1 wherein the composition is dissolved in an aqueous medium and wherein the pH of the aqueous mixture is adjusted to and maintained at from 4.7 to 5.2.

References Cited (Backward Citations)

US3484523A Cited
US3697655A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-02-20 1981-08-22 1982-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-02-20 1985-08-22 1986-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-02-20 1989-08-22 1990-02-21 $7700.00 Window Closed / Lapsed

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