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US4075228A Expired / Lapsed US ⏱️ 0.0 years remaining

1,3-Dithiolane compounds and method of preparation thereof

Assignee: Wyeth Holdings LLC
•
Filing: 1976-09-02
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Granted: 1978-02-21
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Expires: 1996-09-02
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Abstract

Abstract There are provided substituted 1,3-dithiolane compounds and a method for preparing the same. Said 1,3-dithiolane compounds are useful intermediates in the preparation of tetrahydro-7-oxobenzo[b]thien-4-ylureas and tetrahydro-4-oxo-1-naphthylureas which are known animal growth-promoting agents, which thiolanes are represented by the formula: ##STR1## wherein R 1 is a member selected from the group consisting of 2-thienyl and phenyl; R 2 is a member selected from the group consisting of ##STR2## wherein X is chlorine or bromine; R 3 and R 4 are each members selected from the group consisting of hydrogen and methyl; and when R 1 and R 2 are taken together with the carbon atom to which they are attached they represent a bicyclic moiety selected from the group consisting of ##STR3## wherein the carbon atom of said bicyclic moiety marked with an asterisk is also part of the 1,3-dithiolane ring; U is a moiety selected from the group consisting of ##STR4## and when U is ##STR5## said compounds are the racemic mixtures and the optical isomers thereof.

Inventors

  • 👤 William Henry Gastrock
  • 👤 Goro Asato

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 10:03
CPC Classifications
C; C07; C07D; C07D333/00; C07D333/50; C07D333/52; C07D333/54; C07D495/00; C07D495/02; C07D495/10

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 34 words
A 1,3-dithiolane compound of formula: ##STR27## wherein R 3 and R 4 are each hydrogen or methyl; and U is the substituent ##STR28## said compound is the racemic mixture and the optical isomers thereof.
Claim 2
Dependent Claim 34 words
A 1,3-dithiolane compound of formula: ##STR27## wherein R 3 and R 4 are each hydrogen or methyl; and U is the substituent ##STR28## said compound is the racemic mixture and the optical isomers thereof.
Claim 3
Dependent Claim 8 words
The compound according to claim 1, spiro{benzo[b]thiophen-7(6H), 2'-[1,3]dithiolan}-4(5H)-one.
Claim 4
Dependent Claim 14 words
The compound according to claim 1, racemic N-{5,6-dihydrospiro[benzo[b]thiophen-7(4H), 2'-[1,3]dithiolan]-4-yl}formamide and the optical isomers thereof.

References Cited (Backward Citations)

US3803172A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-02-20 1981-08-22 1982-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-02-20 1985-08-22 1986-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-02-20 1989-08-22 1990-02-21 $7700.00 Window Closed / Lapsed

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