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US4074972A Expired / Lapsed US ⏱️ 0.0 years remaining

Urea assay

Assignee: INDIANA DEVELOPMENT FINANCE AUTHORITY
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Filing: 1976-11-10
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Granted: 1978-02-21
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Expires: 1996-11-10
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Abstract

Abstract A urea assay or analysis process and reagents therefor, in which the assay involves a reaction between a sample of biological fluid and an acidic reagent solution of o-phthaldehyde and a chromogenic compound; the chromogenic compounds include certain substituted benzene compounds, certain substituted naphthalene compounds, certain aminopyrimidines, certain substituted quinolines, certain morpholino substituted quinolines and certain morpholino substituted naphthalenes.

Inventors

  • 👤 Jerry W. Denney

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 08:21
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/38; C07D215/42; C07D215/46; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/62; Y; Y10; Y10T; Y10T436/00; Y10T436/17; Y10T436/171538

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 79 words
A process for the quantitation of urea in a fluid sample, in which the sample is reacted with an acidic solution of o-phthalaldehyde and an acidic solution of a chromogenic compound having the following general structure: ##STR7## where R 1 is --H or --CH 3 and where R 2 is --CH 3 or --C 2 H 5 or --H and where R 3 and R 4 are --H or --CH 3 and where n is 1, 2, or 3.
Claim 2
Dependent Claim 79 words
A process for the quantitation of urea in a fluid sample, in which the sample is reacted with an acidic solution of o-phthalaldehyde and an acidic solution of a chromogenic compound having the following general structure: ##STR7## where R 1 is --H or --CH 3 and where R 2 is --CH 3 or --C 2 H 5 or --H and where R 3 and R 4 are --H or --CH 3 and where n is 1, 2, or 3.
Claim 3
Dependent Claim 15 words
The process as defined in claim 1, in which the chromogenic compound used is 8-(4-amino-1-methylbutylamino)-6-methoxyquinoline.
Claim 4
Dependent Claim 90 words
A process for the quantitation of urea in a fluid sample, in which the sample is reacted with a reagent containing an acidic solution of o-phthalaldehyde and an acidic solution of a chromogenic compound of the general class of compounds which have the following general structure: ##STR8## Where R is --H or --CH 3 and where R 1 is --CH 3 , or --CH 2 CH 3 or --H or --CH 2 CH 2 --CH 3 where n is 1, 2, or 3 and where X is O or C.
Claim 5
Dependent Claim 90 words
A process for the quantitation of urea in a fluid sample, in which the sample is reacted with a reagent containing an acidic solution of o-phthalaldehyde and an acidic solution of a chromogenic compound of the general class of compounds which have the following general structure: ##STR8## Where R is --H or --CH 3 and where R 1 is --CH 3 , or --CH 2 CH 3 or --H or --CH 2 CH 2 --CH 3 where n is 1, 2, or 3 and where X is O or C.
Claim 6
Dependent Claim 15 words
The process as defined in claim 3, in which the chromogenic compound used is 8-(2-N-morpholinoethylamino)-6-methoxyquinoline.

References Cited (Backward Citations)

US3091571A Cited
US3890099A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-02-20 1981-08-22 1982-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-02-20 1985-08-22 1986-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-02-20 1989-08-22 1990-02-21 $7700.00 Window Closed / Lapsed

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