US4074039A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hydrophilic N,N-diethyl acrylamide copolymers
Assignee: Czech Academy of Sciences
•
Filing: 1976-02-12
•
Granted: 1978-02-14
•
Expires: 1996-02-12
Abstract
Abstract There is disclosed a hydrophilic gel suitable for exposure to repeated long-term contact with live tissues or mucous membranes and consisting of macromolecules obtained by polymerizing a mixture of at least two copolymerizable units and a crosslinking agent. The mixture consists of from 52 to 99.5 parts by weight of N,N-diethylacrylamide, 43 to 0.1 parts by weight of a member selected from the group consisting of N,N-dialkyl acrylamide, N-alkyl methacrylamide, nitriles of acrylic and methacrylic acids and from 5 to 0.4 parts by of a divinylic monomer selected from the group consisting of diesters of acrylic acid and methacrylic acid, and methylene or ethylene-bis-methacrylamide or acrylamide.
Inventors
- 👤 Drahoslav Lim
- 👤 Jindrich Kopecek
- 👤 Hedvika Bazilova nee Sverinova
- 👤 Jiri Vacik
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:34
CPC Classifications
C; C08; C08F; C08F20/00; C08F20/02; C08F20/52; A; A61; A61L; A61L27/00; A61L27/14; A61L27/16; C08F20/54
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
103 words
A hydrophilic gel for use in exposure to repeated or long term contact with live tissues or mucous membranes and consisting of marcomolecules obtained by polymerizing a mixture consisting of 43 to 0.1 parts by weight of a monomer selected from the group consisting of N-(2-hydroxypropyl) methacrylamide, N,N-dihydroxy ethylacrylamide, N-methyl methacrylamide, N-ethyl methacrylamide, acrylonitrile and methacrylonitrile, 52 to 99.5 parts by weight of N,N-diethyl acrylamide and 5 to 0.4 parts by weight of a crosslinking divinylic monomer selected from the group consisting of glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, methylene-bis-acrylamide and ethylene-bis- methacryl-amide in the presence of a free radical initiator.
Claim 2
Dependent Claim
103 words
A hydrophilic gel for use in exposure to repeated or long term contact with live tissues or mucous membranes and consisting of marcomolecules obtained by polymerizing a mixture consisting of 43 to 0.1 parts by weight of a monomer selected from the group consisting of N-(2-hydroxypropyl) methacrylamide, N,N-dihydroxy ethylacrylamide, N-methyl methacrylamide, N-ethyl methacrylamide, acrylonitrile and methacrylonitrile, 52 to 99.5 parts by weight of N,N-diethyl acrylamide and 5 to 0.4 parts by weight of a crosslinking divinylic monomer selected from the group consisting of glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, methylene-bis-acrylamide and ethylene-bis- methacryl-amide in the presence of a free radical initiator.
Claim 3
Dependent Claim
12 words
The hydrophilic gel of claim 1, wherein said monomer is N,N-dihydroxy ethylacrylamide.
Claim 4
Dependent Claim
11 words
The hydrophilic gel of claim 1, wherein said monomer is methacrylonitrile.
Claim 5
Dependent Claim
12 words
The hydrophilic gel of claim 1, wherein said monomer is N-(2-hydroxypropyl) methacrylamide.
Claim 6
Dependent Claim
11 words
The hydrophilic gel of claim 1, wherein said monomer is acrylonitrile.
Claim 7
Dependent Claim
12 words
The hydrophilic gel of claim 1, wherein said monomer is N-ethyl methacrylamide.
Claim 8
Dependent Claim
12 words
The hydrophilic gel of claim 1, wherein said monomer is N-methyl methacrylamide.
Claim 9
Dependent Claim
13 words
The hydrophilic gel of claim 1, wherein said divinylic monomer is tri-glycol dimethacrylate.
Claim 10
Dependent Claim
12 words
The hydrophilic gel of claim 1, wherein said divinylic monomer is methylene-bis-acrylamide.
Claim 11
Dependent Claim
182 words
A hydrophilic gel for use in exposure to repeated or long term contact with live tissues or mucous membranes and consisting of macromolecules obtained by polymerizing a mixture consisting of 43 to 0.1 parts by weight of a monomer selected from the group consisting of N,N-dialkyl methacrylamide, N,N-dialkyl acrylamide, N-alkyl methacrylamide, acrylonitrile and methacrylonitrile, 52 to 99.5 parts by weight of N,N-diethyl acrylamide and 5 to 0.4 parts by weight of a crosslinking divinylic monomer selected from the group consisting of glycol dimethacrylate, triethylene glycol dimethacrylate, diethylene glycol dimethacrylate, and methylene or ethylene-bis-acrylamide or methacrylamide, wherein the alkyl moiety has from 1 to 6 carbons, except that in N,N-dialkyl acrylamide the alkyl group is other than ethyl, and wherein the alkyl moiety of said dialkyl methacrylamide and acrylamide may be substituted with at least one radical selected from the group consisting of hydroxyl, polyhydroxyalkyl and amine and the alkyl moiety of said alkyl methacrylamide may be substituted with a hydroxyl group, in the presence of a free radical initiator at a temperature of 20° to 85° C. for at least 7 hours.
Claim 12
Dependent Claim
182 words
A hydrophilic gel for use in exposure to repeated or long term contact with live tissues or mucous membranes and consisting of macromolecules obtained by polymerizing a mixture consisting of 43 to 0.1 parts by weight of a monomer selected from the group consisting of N,N-dialkyl methacrylamide, N,N-dialkyl acrylamide, N-alkyl methacrylamide, acrylonitrile and methacrylonitrile, 52 to 99.5 parts by weight of N,N-diethyl acrylamide and 5 to 0.4 parts by weight of a crosslinking divinylic monomer selected from the group consisting of glycol dimethacrylate, triethylene glycol dimethacrylate, diethylene glycol dimethacrylate, and methylene or ethylene-bis-acrylamide or methacrylamide, wherein the alkyl moiety has from 1 to 6 carbons, except that in N,N-dialkyl acrylamide the alkyl group is other than ethyl, and wherein the alkyl moiety of said dialkyl methacrylamide and acrylamide may be substituted with at least one radical selected from the group consisting of hydroxyl, polyhydroxyalkyl and amine and the alkyl moiety of said alkyl methacrylamide may be substituted with a hydroxyl group, in the presence of a free radical initiator at a temperature of 20° to 85° C. for at least 7 hours.
References Cited (Backward Citations)
GB831881A
Cited
US3660545A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-02-13 | 1981-08-15 | 1982-02-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-02-13 | 1985-08-15 | 1986-02-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-02-13 | 1989-08-15 | 1990-02-14 | $7700.00 | Window Closed / Lapsed |