US4071536A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antibiotics
Assignee: Beecham Group PLC
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Filing: 1976-05-07
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Granted: 1978-01-31
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Expires: 1996-05-07
Abstract
Abstract An active antibacterial substance from Pseudomonas fluorescens bacterium designated pseudomonic acid and as a coproduct a minor amount of a compound having an additional OH group designated as pseudomonic acid I. These two substances obtained are separated and purified. Alkali metal salts and methyl esters can be prepared. The antibacterial activity of pseudomonic acid appears to reside in the free acid from which results from in vivo hydrolysis of the methyl ester which is crystalline.
Inventors
- 👤 Kevin David Barrow
- 👤 Graham Mellows
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 15:44
CPC Classifications
C; C07; C07D; C07D407/00; C07D407/02; C07D407/06; A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; C07D309/00; C07D309/02; C07D309/08; C07D309/10; C12; C12P; C12P17/00; C12P17/02; C12P17/06; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/874; Y10S435/876
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
39 words
A compound which is the free acid form of pseudomonic acid having the formula (I) or an alkali metal salt or methyl ester of the carboxylic acid group thereof : ##STR5## , the double bond being in the trans-configuration.
Claim 2
Dependent Claim
39 words
A compound which is the free acid form of pseudomonic acid having the formula (I) or an alkali metal salt or methyl ester of the carboxylic acid group thereof : ##STR5## , the double bond being in the trans-configuration.
Claim 3
Dependent Claim
11 words
The pseudomonic acid of claim 1, in its free acid form.
Claim 4
Dependent Claim
10 words
The methyl ester of the pseudomonic acid of claim 1.
Claim 5
Dependent Claim
13 words
The sodium salt of the pseudomonic acid of formula (I) of claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-30 | 1981-08-01 | 1982-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-30 | 1985-08-01 | 1986-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-30 | 1989-08-01 | 1990-01-31 | $7700.00 | Window Closed / Lapsed |