US4071519A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1-Carbamoyl-5-fluorouracil derivatives
Assignee: Mitsui Toatsu Chemicals Inc
•
Filing: 1975-11-05
•
Granted: 1978-01-31
•
Expires: 1995-11-05
Abstract
Abstract 1-Carbamoyl-5-fluorouracil derivatives represented by the formula <IMAGE> wherein R represents alkyl containing 3-8 carbon atoms are effective oral anti-tumor agents with low toxicity.
Inventors
- 👤 Shoichiro Ozaki
- 👤 Haruki Mori
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 18:40
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/52; C07D239/54; C07D239/545; C07D239/553; A; A61; A61P; A61P35/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
13 words
A 1-carbamoyl-5-fluorouracil compound having the formula ##STR5## wherein R represents C 3-8 alkyl.
Claim 2
Dependent Claim
13 words
A 1-carbamoyl-5-fluorouracil compound having the formula ##STR5## wherein R represents C 3-8 alkyl.
Claim 3
Dependent Claim
22 words
The compound of claim 1 wherein R is an alkyl selected from the group consisting of n-propyl, i-propyl, n-butyl, t-butyl and n-hexyl.
Claim 4
Dependent Claim
1 words
1-(n-hexylcarbamoyl)-5-fluorouracil.
Claim 5
Dependent Claim
1 words
1-(n-hexylcarbamoyl)-5-fluorouracil.
Claim 6
Dependent Claim
1 words
1-(n-propylcarbamoyl)-5-fluorouracil.
Claim 7
Dependent Claim
1 words
1-(n-propylcarbamoyl)-5-fluorouracil.
Claim 8
Dependent Claim
1 words
1-(t-butylcarbamoyl)-5-fluorouracil.
Claim 9
Dependent Claim
1 words
1-(t-butylcarbamoyl)-5-fluorouracil.
Claim 10
Dependent Claim
1 words
1-(n-butylcarbamoyl)-5-fluorouracil.
Claim 11
Dependent Claim
1 words
1-(n-butylcarbamoyl)-5-fluorouracil.
Claim 12
Dependent Claim
1 words
1-(i-propylcarbamoyl)-5-fluorouracil.
Claim 13
Dependent Claim
1 words
1-(i-propylcarbamoyl)-5-fluorouracil.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-30 | 1981-08-01 | 1982-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-30 | 1985-08-01 | 1986-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-30 | 1989-08-01 | 1990-01-31 | $7700.00 | Window Closed / Lapsed |