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US4066757A Expired / Lapsed US ⏱️ 0.0 years remaining

Oral contraceptive regimen

Assignee: Ortho Pharmaceutical Corp
•
Filing: 1973-03-26
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Granted: 1978-01-03
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Expires: 1993-03-26
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Abstract

Abstract An oral contraceptive regimen in which a progestin is administered from the fifth through the twenty-fifth day of the physiological cycle is described. The amount of progestin administered is serially increased during the period of administration; regular menses occurs when administration of the regimen is complete.

Inventors

  • 👤 Samuel A. Pasquale

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 20:31
CPC Classifications
A; A61; A61K; A61K45/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 79 words
In a method for the prevention of conception of the type wherein a progestin is administered to the human female serially over at least the fifth through the twenty-fifth day of the cycle, the improvement consisting of: administering a substantially higher dose of a progestin during approximately the last 7 days of administration than during approximately the first 7 days of administration and terminating the administration of the progestational agent on or after the twenty-fifth day of the cycle.
Claim 2
Dependent Claim 79 words
In a method for the prevention of conception of the type wherein a progestin is administered to the human female serially over at least the fifth through the twenty-fifth day of the cycle, the improvement consisting of: administering a substantially higher dose of a progestin during approximately the last 7 days of administration than during approximately the first 7 days of administration and terminating the administration of the progestational agent on or after the twenty-fifth day of the cycle.
Claim 3
Dependent Claim 78 words
In a method for the prevention of conception of the type wherein a progestin is administered to the human female serially over at least the fifth through the twenty-fifth day of the cycle, the improvement consisting of: serially increasing the dose of progestin substantially over the course of administration to thus produce an increasing gradient in the circulating progestin level and then terminating the administration of the progestational agent on or after the twenty-fifth day of the cycle.
Claim 4
Dependent Claim 78 words
In a method for the prevention of conception of the type wherein a progestin is administered to the human female serially over at least the fifth through the twenty-fifth day of the cycle, the improvement consisting of: serially increasing the dose of progestin substantially over the course of administration to thus produce an increasing gradient in the circulating progestin level and then terminating the administration of the progestational agent on or after the twenty-fifth day of the cycle.
Claim 5
Dependent Claim 32 words
The method of claim 1 wherein the dose administered at the end of the cycle is at least twice the dose administered over the fifth through the twelfth day of the cycle.
Claim 6
Dependent Claim 52 words
The method of claim 1 wherein the dosage of the progestational agent during the second week of the regimen is at least double the dosage administered during the first week, and the dosage administered during the third week is at least double the dosage administered during the second week of the regimen.
Claim 7
Dependent Claim 10 words
The method of claim 1 wherein the progestin is 17α-ethynyl-17β-acetoxy-19-norandrost-4-en-3-one-oxime.
Claim 8
Dependent Claim 10 words
The method of claim 1 wherein the progestin is norethindrone.

References Cited (Backward Citations)

US3568828A Cited
US3409721A Cited
US3639600A Cited
US3733407A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-01-02 1981-07-04 1982-01-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-01-02 1985-07-04 1986-01-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-01-02 1989-07-04 1990-01-03 $7700.00 Window Closed / Lapsed

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