US4066549A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for the precipitation of human blood plasma components
Assignee: Blutspendedienst der Landsverbande des Deutschen Roten Kreuses
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Filing: 1975-09-18
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Granted: 1978-01-03
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Expires: 1995-09-18
Abstract
Abstract A process and apparatus for the precipitation of human blood plasma components characterized in that the initial blood plasma and the precipitating agent are continuously introduced into a precipitation container in an adjusted relationship but separated with simultaneous control of the required pH values. The suspension of the individual precipitants is conveyed across a delay station and then separated. The delay station includes a flow passageway connecting the precipitation container to a separating means, with the flow passageway being so constructed as to permit substantially laminar flow of fluid therethrough. Means are also present in the flow passageway for changing the residence time of fluid therein by permitting selective variation of the length of the flow passageway.
Inventors
- 👤 Henning Oeser
- 👤 Ulrich Ahrens
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 17:24
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/12; A61K35/14; A61K35/16; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/83
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
160 words
An apparatus for the continuous precipitation of human blood plasma components comprising: individual supply containers for blood plasma, a precipitation agent and a buffer solution, a precipitation vessel, means for conveying the blood plasma and the precipitation agent from the respective supply containers to said precipitation vessel and including means for combining the blood plasma and precipitating agent immediately upstream of said precipitation vessel, means for conveying the buffer solution from its respective supply container to said precipitation vessel, means for cooling said precipitation vessel and the contents thereof, means for causing turbulence in said precipitation vessel, a flow passageway connecting said precipitation vessel and centrifuge means, said flow passageway being so constructed as to permit substantially laminar flow of fluid therethrough, means for selectively changing the residence time of fluid in said flow passageway by varying the length of said flow passageway through which fluid is caused to flow, and means for removing the centrifugate from said centrifuge means.
Claim 2
Independent Claim
160 words
An apparatus for the continuous precipitation of human blood plasma components comprising: individual supply containers for blood plasma, a precipitation agent and a buffer solution, a precipitation vessel, means for conveying the blood plasma and the precipitation agent from the respective supply containers to said precipitation vessel and including means for combining the blood plasma and precipitating agent immediately upstream of said precipitation vessel, means for conveying the buffer solution from its respective supply container to said precipitation vessel, means for cooling said precipitation vessel and the contents thereof, means for causing turbulence in said precipitation vessel, a flow passageway connecting said precipitation vessel and centrifuge means, said flow passageway being so constructed as to permit substantially laminar flow of fluid therethrough, means for selectively changing the residence time of fluid in said flow passageway by varying the length of said flow passageway through which fluid is caused to flow, and means for removing the centrifugate from said centrifuge means.
Claim 3
Dependent Claim
34 words
An apparatus as in claim 1 and wherein: said flow passageway is arranged in a sinusoidal path and includes valve means for selecting that portion of the flow passageway through which fluid may flow.
Claim 4
Dependent Claim
29 words
An apparatus as in claim 2 and including: an intermediate container provided near the end of said flow passageway and means connecting said intermediate container and said centrifuge means.
Claim 5
Dependent Claim
49 words
An apparatus as in claim 2 and including: a centrifugate receiving container connected to said centrifuge means, a second said apparatus for precipitation of human blood plasma components connected in series, said centrifugate receiving container of the first apparatus comprising the blood plasma supply container for the second apparatus.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-02 | 1981-07-04 | 1982-01-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-02 | 1985-07-04 | 1986-01-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-02 | 1989-07-04 | 1990-01-03 | $7700.00 | Window Closed / Lapsed |