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US4066412A Expired / Lapsed US ⏱️ 0.0 years remaining

Automatic clinical analyzer

Assignee: EIDP Inc
•
Filing: 1968-08-16
•
Granted: 1978-01-03
•
Expires: 1988-08-16
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Abstract

Abstract An apparatus for automatically performing analytic procedural steps on a fluid contained in a disposable deformable test pack. The apparatus consists of a means for filling the test pack with sample fluid, a means for controlling the environment of the test pack, a means for initiating reactions within the test pack, a means for analyzing the fluid in the test pack, and a transport means designed to hold the test pack and to transport it between the various operating stations. Associated circuitry combining method switchng and control logic make the operation of the instrument fully automatic.

Inventors

  • 👤 Donald R. Johnson
  • 👤 Richard G. Nadeau
  • 👤 Gerrit Nieuweboer
  • 👤 William L. Truett

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 18:44
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/54; B01L3/545; B01L3/5453; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N35/00; G01N35/02; G01N35/021; G01N35/04; G01N2035/0401; G01N2035/0429; G01N2035/0436; G01N35/10; G01N35/1079

Claims Analysis

Total Claims: 76
Claim 1
Independent Claim 178 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing disposable chemical testing containers; means to transfer at least a portion of a sample from a sample storage site to a reaction compartment within one of the plurality of disposable containers; at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the disposable container; said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture; and means to advance said carrying means through said sample transfer and reagent addition means to said monitoring means.
Claim 2
Dependent Claim 178 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing disposable chemical testing containers; means to transfer at least a portion of a sample from a sample storage site to a reaction compartment within one of the plurality of disposable containers; at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the disposable container; said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture; and means to advance said carrying means through said sample transfer and reagent addition means to said monitoring means.
Claim 3
Dependent Claim 40 words
The automated analytical apparatus of claim 1 further including means to incubate the reaction mixture within the reaction compartment of the disposable container for a period of time sufficient to bring the reaction mixture to the desired state for analysis.
Claim 4
Dependent Claim 19 words
The automated analytical apparatus of claim 1 further including means to dilute a particular sample to the appropriate concentration.
Claim 5
Dependent Claim 25 words
The automated analytical apparatus of claim 1 wherein said means to transfer sample portions includes means to dilute the sample portion to the appropriate concentration.
Claim 6
Dependent Claim 26 words
The automated analytical apparatus of claim 1 wherein said sample transfer means includes means to inject the sample into the reaction compartment of the disposable container.
Claim 7
Dependent Claim 29 words
The automated analytical apparatus of claim 1 wherein said reagent addition means includes means to place the reagent-storing chambers of the disposable container in communication with the reaction compartment.
Claim 8
Dependent Claim 23 words
The automated analytical apparatus of claim 1 further including additional reagent addition means further along the path of travel of said carrying means.
Claim 9
Dependent Claim 34 words
The automated analytical apparatus of claim 1 further including means to eject a used disposable container into a disposable zone after the disposable container has passed through the monitoring means for the last time.
Claim 10
Dependent Claim 21 words
The automated analytical apparatus of claim 1 further including additional monitoring means associated with said apparatus in said sample transfer means.
Claim 11
Dependent Claim 40 words
The automated analytical apparatus of claim 1 further including means to identify a particular disposable container as containing a sample from a particular patient and to correlate the analytical data obtained by said monitoring means with the patient identification data.
Claim 12
Dependent Claim 31 words
The automated analytical apparatus of claim 1 further including at least one additional means for the addition of at least one reagent stored within the disposable container to the reaction compartment.
Claim 13
Dependent Claim 15 words
The automated analytical apparatus of claim 1 wherein there are a plurality of monitoring means.
Claim 14
Dependent Claim 164 words
An automated analytical apparatus comprising a magazine for the storage of a plurality of different disposable reaction containers, means to add a material to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the disposable container, said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture; and means to transport the disposable container from said magazine through said material addition means and said reagent addition means to said monitoring means.
Claim 15
Dependent Claim 164 words
An automated analytical apparatus comprising a magazine for the storage of a plurality of different disposable reaction containers, means to add a material to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the disposable container, said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture; and means to transport the disposable container from said magazine through said material addition means and said reagent addition means to said monitoring means.
Claim 16
Dependent Claim 31 words
The automated analytical apparatus of claim 13 further including at least one additional means for the addition of at least one reagent stored within said disposable container to the reaction compartment.
Claim 17
Dependent Claim 212 words
An automated analytical apparatus adapted for use with reagent-storing disposable reaction containers, each of the containers being carried by a support member and being sectioned into a reaction compartment and a plurality of reagent storage compartments, the compartments being separated from each other by walls weakly bonded to the supporting carrier so that the compartments can be brought into communication upon destruction of the weak bonds; said apparatus comprising means to add a sample to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment, said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture, and means to transport the disposable container through said sample addition means and said reagent addition means to said monitoring means.
Claim 18
Dependent Claim 212 words
An automated analytical apparatus adapted for use with reagent-storing disposable reaction containers, each of the containers being carried by a support member and being sectioned into a reaction compartment and a plurality of reagent storage compartments, the compartments being separated from each other by walls weakly bonded to the supporting carrier so that the compartments can be brought into communication upon destruction of the weak bonds; said apparatus comprising means to add a sample to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment, said monitoring means including light source means and means responsive to the magnitude of light absorbed by the reaction mixture as light is transmitted therethrough from said light source means, said monitoring means further including means to compress said disposable container between said light source means and said responsive means during analysis to define a fixed optical path length through the reaction mixture, and means to transport the disposable container through said sample addition means and said reagent addition means to said monitoring means.
Claim 19
Dependent Claim 28 words
The automated analytical apparatus of claim 15 wherein said reagent addition means includes means to manipulate the weak bonds separating the reagent storage compartments from the reaction compartment.
Claim 20
Dependent Claim 27 words
The automated analytical apparatus of claim 16 further including means to reinforce a particular weak bond while another weak bond is being destroyed by said manipulation means.
Claim 21
Dependent Claim 31 words
The automated analytical apparatus of claim 15 further including at least one additional means for the addition of at least one reagent stored within the disposable container to the reaction compartment.
Claim 22
Dependent Claim 47 words
The automated analytical apparatus of claim 15 further including a magazine for the storage of a plurality of said disposable containers, said transport means being adapted to transport each of said disposable containers from said magazine through said sample and reagent addition means to said monitoring means.
Claim 23
Dependent Claim 138 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers having at least one flexible wall; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; means for the addition of at least one reagent stored within the disposable container to the reaction compartment; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; said monitoring means including means to cooperate with the flexible wall or walls of said reaction compartment to define a fixed optical path through the reaction mixture therein; and means to advance said carrying means through said sample transfer and reagent addition means to said monitoring means.
Claim 24
Dependent Claim 138 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers having at least one flexible wall; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; means for the addition of at least one reagent stored within the disposable container to the reaction compartment; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; said monitoring means including means to cooperate with the flexible wall or walls of said reaction compartment to define a fixed optical path through the reaction mixture therein; and means to advance said carrying means through said sample transfer and reagent addition means to said monitoring means.
Claim 25
Dependent Claim 29 words
The automated analytical apparatus of claim 20 wherein said reagent addition means includes means to place the reagent-storing chambers of the disposable container in communication with the reaction compartment.
Claim 26
Dependent Claim 50 words
The automated analytical apparatus of claim 20 wherein each reagent is stored in a storage chamber separated from the reaction compartment by walls weakly bonded to a supporting carrier, and said reagent addition means includes means to manipulate the weak bonds separating the reagent storage chamber from the reaction compartment.
Claim 27
Dependent Claim 44 words
The automated analytical apparatus of claim 20 further including means to reinforce a particular weak bond separating one reagent chamber from the reaction compartment while another weak bond separating a different reagent chamber from the reaction compartment is being destroyed by said manipulation means.
Claim 28
Dependent Claim 32 words
The automated analytical apparatus of claim 20 further including at least one additional means for the addition of at least one further reagent stored within the disposable container to a reaction compartment.
Claim 29
Dependent Claim 101 words
An automated analytical apparatus comprising a magazine for the storage of a plurality of different disposable reaction containers, means to add a material to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within said disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the disposable container, and means to transport the disposable container from said magazine through said material addition means and said reagent addition means to said monitoring means.
Claim 30
Dependent Claim 101 words
An automated analytical apparatus comprising a magazine for the storage of a plurality of different disposable reaction containers, means to add a material to be analyzed to a reaction compartment within a disposable container, at least one means for the addition of at least one reagent stored within said disposable container to the reaction compartment forming a reaction mixture, means to monitor at least one of the physical properties of the reaction mixture within the disposable container, and means to transport the disposable container from said magazine through said material addition means and said reagent addition means to said monitoring means.
Claim 31
Dependent Claim 31 words
The automated analytical apparatus of claim 25 further including at least one additional means for the addition of at least one reagent stored within said disposable container to the reaction compartment.
Claim 32
Dependent Claim 121 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to manipulate at least one weak bond separating a reagent storage compartment from said reaction compartment to thereby place the reagent compartment in communication with the reaction compartment, and means to reinforce at least one other of said weak bonds while said other weak bond is being destroyed by said manipulation means.
Claim 33
Dependent Claim 121 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to manipulate at least one weak bond separating a reagent storage compartment from said reaction compartment to thereby place the reagent compartment in communication with the reaction compartment, and means to reinforce at least one other of said weak bonds while said other weak bond is being destroyed by said manipulation means.
Claim 34
Dependent Claim 22 words
The means of claim 27 wherein said manipulation means comprises means to promote flexing of the opposed faces of said weak bonds.
Claim 35
Dependent Claim 29 words
The means of claim 27 wherein said manipulation means comprises means to cause one layer of said weak bond to separate from the opposing layer of said weak bond.
Claim 36
Dependent Claim 29 words
The means of claim 28 wherein said manipulation means comprises means to cause one layer of said weak bond to separate from the opposing layer of said weak bond.
Claim 37
Dependent Claim 131 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to place at least one reagent compartment in communication with the reaction compartment and means to initially prevent such communication as to at least one other of said reagent compartments by reinforcing said weak bond adjacent thereto while said other weak bond adjacent the reagent compartment being placed in communication with the reaction compartment is being destroyed by said communication promoting means.
Claim 38
Dependent Claim 131 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to place at least one reagent compartment in communication with the reaction compartment and means to initially prevent such communication as to at least one other of said reagent compartments by reinforcing said weak bond adjacent thereto while said other weak bond adjacent the reagent compartment being placed in communication with the reaction compartment is being destroyed by said communication promoting means.
Claim 39
Dependent Claim 131 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to place at least one reagent compartment in communication with the reaction compartment and means to initially prevent such communication as to at least one other of said reagent compartments by reinforcing said weak bond adjacent thereto while said other weak bond adjacent the reagent compartment being placed in communication with the reaction compartment is being destroyed by said communication promoting means.
Claim 40
Dependent Claim 131 words
Means to dispense a plurality of reagents from their storage sites in a disposable reaction container, each container being sectioned into a reaction compartment and a plurality of reagent storage compartments, the reaction compartment being separated from each storage compartment by a weak bond so that upon destruction of said weak bond the reaction compartment and the storage compartment can be brought into communication, said dispensing means comprising means to place at least one reagent compartment in communication with the reaction compartment and means to initially prevent such communication as to at least one other of said reagent compartments by reinforcing said weak bond adjacent thereto while said other weak bond adjacent the reagent compartment being placed in communication with the reaction compartment is being destroyed by said communication promoting means.
Claim 41
Dependent Claim 116 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer at least a portion of a sample from a sample storage site to a reaction compartment within one of the plurality of disposable containers; at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 42
Dependent Claim 116 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer at least a portion of a sample from a sample storage site to a reaction compartment within one of the plurality of disposable containers; at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 43
Dependent Claim 39 words
The automated analytical apparatus of claim 33 including means to incubate the reaction mixture within the reaction compartment of the disposable container for a period of time sufficient to bring the reaction mixture to the desired state for analysis.
Claim 44
Dependent Claim 26 words
The automated analytical apparatus of claim 33 wherein said means to transfer sample portions includes means to dilute the sample portion added to an appropriate concentration.
Claim 45
Dependent Claim 28 words
The automated analytical apparatus of claim 33 wherein said reagent addition means includes means to place reagent-storing chambers of the disposable container in communication with the reaction compartment.
Claim 46
Dependent Claim 23 words
The automated analytical apparatus of claim 33 further including additional reagent addition means further along the path of travel of said carrying means.
Claim 47
Dependent Claim 30 words
The automated analytical apparatus of claim 33 further including means to feed a used disposable container into an output station after the disposable container has passed through the monitoring means.
Claim 48
Dependent Claim 21 words
The automated analytical apparatus of claim 33 further including additional monitoring means associated with said apparatus in said sample transfer means.
Claim 49
Dependent Claim 38 words
The automated analytical apparatus of claim 33 further including means to identify a particular disposable container as being from a particular patient and to correlate the analytical data obtained by said monitoring means with the patient identification data.
Claim 50
Dependent Claim 31 words
The automated analytical apparatus of claim 33 further including at least one additional means for the addition of at least one reagent stored within the disposable container to the reaction compartment.
Claim 51
Dependent Claim 26 words
The automated analytical apparatus of claim 33 wherein said sample transfer means includes means to inject the sample into the reaction compartment of the disposable container.
Claim 52
Dependent Claim 51 words
The automated analytical apparatus of claim 33 wherein said monitoring means includes a light source and a detection means, said detection means being positioned on the opposite side of the reaction mixture from said light source, said detection means being responsive to light transmittance of the constituents in each reaction mixture.
Claim 53
Dependent Claim 110 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; means for the sequential addition of a plurality of reagents stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 54
Dependent Claim 110 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; means for the sequential addition of a plurality of reagents stored within the disposable container to the reaction compartment forming a reaction mixture; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 55
Dependent Claim 130 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; first means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; second means for the addition of at least one further reagent stored within the disposable container to the reaction compartment; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 56
Dependent Claim 130 words
An automated analytical apparatus comprising means to carry a plurality of reagent-storing, disposable chemical testing containers; means to transfer a sample aliquot from a sample storage site to a reaction compartment within one of the plurality of disposable containers; first means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture; second means for the addition of at least one further reagent stored within the disposable container to the reaction compartment; means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment; and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 57
Dependent Claim 175 words
An automated analytical apparatus adapted for use with reagent-storing disposable chemical testing containers, each of said containers being carried by a support member and being sectioned into a reaction compartment and a plurality of reagent storage compartments, said compartments being separated from each other by walls weakly bonded to the supporting carrier so that said compartments can be brought into communication upon destruction of the weak bonds; said apparatus comprising means to carry a plurality of said disposable containers, means to transfer a sample aliquot from a sample storage site to the reaction compartment within one of said plurality of disposable containers, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment, and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 58
Dependent Claim 175 words
An automated analytical apparatus adapted for use with reagent-storing disposable chemical testing containers, each of said containers being carried by a support member and being sectioned into a reaction compartment and a plurality of reagent storage compartments, said compartments being separated from each other by walls weakly bonded to the supporting carrier so that said compartments can be brought into communication upon destruction of the weak bonds; said apparatus comprising means to carry a plurality of said disposable containers, means to transfer a sample aliquot from a sample storage site to the reaction compartment within one of said plurality of disposable containers, at least one means for the addition of at least one reagent stored within the disposable container to the reaction compartment forming a reaction mixture, means further along the path of travel of said carrying means to monitor at least one of the physical properties of the reaction mixture within the reaction compartment, and means to advance said carrying means through said sample transfer means and reagent addition means to said monitoring means.
Claim 59
Dependent Claim 28 words
The automated analytical apparatus of claim 46 wherein said reagent addition means includes means to manipulate the weak bonds separating the reagent storage compartments from the reaction compartment.
Claim 60
Dependent Claim 27 words
The automated analytical apparatus of claim 46 further including means to reinforce a particular weak bond while another weak bond is being destroyed by said mainipulation means.
Claim 61
Dependent Claim 31 words
The automated analytical apparatus of claim 46 further including at least one additional means for the addition of at least one reagent stored within the disposable container to the reaction compartment.
Claim 62
Dependent Claim 45 words
The automated analytical apparatus of claim 46 further including a magazine for the storage of a plurality of said disposable containers, said carrying means being adapted to advance said disposable containers from said magazine through said sample and reagent addition means to said monitoring means.
Claim 63
Dependent Claim 185 words
An automated analytical system including a disposable reaction container comprising at least one compartment for the admixing of materials added thereto, a storage section having at least one separate reagent storage chamber adapted for communication with each of said admixing compartments, and restraining means to prevent the premature movement of prepackaged reagents from said storage chambers, at least a portion of said admixing compartment being sufficiently optically transparent so that said compartment can be utilized as an optical cell for optical analysis, a station for the addition of a measured quantity of a sample from a sample storage site to at least one of said admixing compartments, at least one station for the addition of at least one reagent stored within said disposable container to at least one of said admixing compartments forming a reaction mixture, a readout station for monitoring at least one of the physical properties of the reaction mixture within the admixing compartment and deriving a final analytical result based upon the information obtained therefrom, and means to route said disposable reaction container through each of said stations to said readout station.
Claim 64
Dependent Claim 185 words
An automated analytical system including a disposable reaction container comprising at least one compartment for the admixing of materials added thereto, a storage section having at least one separate reagent storage chamber adapted for communication with each of said admixing compartments, and restraining means to prevent the premature movement of prepackaged reagents from said storage chambers, at least a portion of said admixing compartment being sufficiently optically transparent so that said compartment can be utilized as an optical cell for optical analysis, a station for the addition of a measured quantity of a sample from a sample storage site to at least one of said admixing compartments, at least one station for the addition of at least one reagent stored within said disposable container to at least one of said admixing compartments forming a reaction mixture, a readout station for monitoring at least one of the physical properties of the reaction mixture within the admixing compartment and deriving a final analytical result based upon the information obtained therefrom, and means to route said disposable reaction container through each of said stations to said readout station.
Claim 65
Dependent Claim 34 words
The automated analytical system of claim 51 further including a second station for the addition of at least one further reagent stored within said disposable container to at least one of said admixing compartments.
Claim 66
Dependent Claim 52 words
The automated analytical system of claim 51 wherein said disposable reaction container has a single admixing compartment and a plurality of separate reagent storage chambers associated therewith, said system further including a second station for the addition of at least one further reagent stored within said disposable container to said admixing component.
Claim 67
Dependent Claim 187 words
An automated analytical system including: a disposable reaction container comprising a reaction compartment for the mixing of materials added thereto, a storage section having a plurality of separate reagent storage chambers, said reagent storage chambers being adapted to be charged with predetermined quantities of reagents, each of said reagent storage chambers being further adapted to release said reagents independently of any other reagents present in other reagent storage chambers into said reaction compartment, and means communicating with said reaction compartment for introducing a sample into said reaction compartment, at least a portion of said reaction compartment being sufficiently optically transparent so that said reaction compartment can be utilized as an optical cell for optical analysis; a station for the addition of sample to an admixing compartment; at least one station for the addition of at least one reagent stored within said disposable container to said admixing compartment forming a reaction mixture; a readout station for monitoring at least one of the physical properties of the reaction mixture within said disposable container; and means to route said disposable container through each of said stations to said readout station.
Claim 68
Dependent Claim 187 words
An automated analytical system including: a disposable reaction container comprising a reaction compartment for the mixing of materials added thereto, a storage section having a plurality of separate reagent storage chambers, said reagent storage chambers being adapted to be charged with predetermined quantities of reagents, each of said reagent storage chambers being further adapted to release said reagents independently of any other reagents present in other reagent storage chambers into said reaction compartment, and means communicating with said reaction compartment for introducing a sample into said reaction compartment, at least a portion of said reaction compartment being sufficiently optically transparent so that said reaction compartment can be utilized as an optical cell for optical analysis; a station for the addition of sample to an admixing compartment; at least one station for the addition of at least one reagent stored within said disposable container to said admixing compartment forming a reaction mixture; a readout station for monitoring at least one of the physical properties of the reaction mixture within said disposable container; and means to route said disposable container through each of said stations to said readout station.
Claim 69
Dependent Claim 48 words
The automated analytical system of claim 54 further including at least one station for mixing and incubation wherein the reaction mixture is maintained within the admixing compartment of the disposable container for a period of time sufficient to bring the reaction mixture to the desired state for analysis.
Claim 70
Dependent Claim 23 words
The automated analytical system of claim 54 including a station for the dilution of a sample to be analyzed to an appropriate concentration.
Claim 71
Dependent Claim 14 words
The automated analytical system of claim 54 having a plurality of reagent addition stations.
Claim 72
Dependent Claim 15 words
The automated analytical system of claim 54 wherein said disposable container has data stored thereon.
Claim 73
Dependent Claim 150 words
An automated system for analyzing a fluid sample contained within a disposable test pack comprising: at least one sample container containing a sample fluid; at least one disposable test pack adapted to serve as an optical cuvette having a portion adapted to receive said sample fluid, a portion adapted to store at least one reagent separate from said sample fluid receiving portion, and communicating means adapted to introduce sample fluid into said sample fluid receiving portion; a filling means adapted to aliquot the sample fluid from the sample fluid container through said communicating means to said sample fluid receiving portion; reaction originating means adapted to mix at least one reagent from said reagent storage portion with said sample fluid in said test pack; means for optical measurement of the sample fluid-reagent mixture while it is in said test pack; and means to readout the measurement of the sample fluid-reagent mixture.
Claim 74
Dependent Claim 150 words
An automated system for analyzing a fluid sample contained within a disposable test pack comprising: at least one sample container containing a sample fluid; at least one disposable test pack adapted to serve as an optical cuvette having a portion adapted to receive said sample fluid, a portion adapted to store at least one reagent separate from said sample fluid receiving portion, and communicating means adapted to introduce sample fluid into said sample fluid receiving portion; a filling means adapted to aliquot the sample fluid from the sample fluid container through said communicating means to said sample fluid receiving portion; reaction originating means adapted to mix at least one reagent from said reagent storage portion with said sample fluid in said test pack; means for optical measurement of the sample fluid-reagent mixture while it is in said test pack; and means to readout the measurement of the sample fluid-reagent mixture.
Claim 75
Dependent Claim 98 words
An automated analytical system for analyzing a fluid sample contained in a disposable test pack, said pack having means for receiving said sample into said pack and having at least one reagent stored within said pack but separated from said sample, said pack being sequentially passed through a plurality of processing stations comprising: a station for mixing at least one reagent stored within said pack with said fluid sample; a station for the measurement of at least one property of the sample-reagent mixture while it is in said test pack; and a station for readout of said measurement.
Claim 76
Dependent Claim 98 words
An automated analytical system for analyzing a fluid sample contained in a disposable test pack, said pack having means for receiving said sample into said pack and having at least one reagent stored within said pack but separated from said sample, said pack being sequentially passed through a plurality of processing stations comprising: a station for mixing at least one reagent stored within said pack with said fluid sample; a station for the measurement of at least one property of the sample-reagent mixture while it is in said test pack; and a station for readout of said measurement.

References Cited (Backward Citations)

US2797149A Cited
US3266298A Cited
US3476515A Cited
US3497320A Cited
US3504376A Cited
US3477822A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-01-02 1981-07-04 1982-01-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-01-02 1985-07-04 1986-01-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-01-02 1989-07-04 1990-01-03 $7700.00 Window Closed / Lapsed

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