Device for measuring and recording spontaneous blood platelet aggregation in platelet-rich citrated plasma

Claim 1

A device for the photometric measuring of the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma, comprising a photometer including a light source and a photo cell aligned with the light source to receive light rays therefrom, a light filter positioned between the light source and photo cell, a diaphragm having an aperture formed therein in a predetermined position and located between said filter and photo cell whereby the aperture in the diaphragm passes a well defined column of light rays from the light source to the photo cell; a hollow disc cuvette rotatably mounted in the photometer between said diaphragm and photocell for rotation in a vertical plane with its central axis in a horizontal plane, said vertical plane being located in and transverse to the path of light rays passing through the diaphragm, said cuvette containing a supply of citrated plasma to be measured; means for heating said disc cuvette to a predetermined temperature; and means for rotating said disc cuvette at a speed of between 10 and 60 revolutions per minute; said disc cuvette being located in the photometer at a position with respect to said diaphragm wherein the light rays from the diaphragm pass through a lower quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 2

A device for the photometric measuring of the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma, comprising a photometer including a light source and a photo cell aligned with the light source to receive light rays therefrom, a light filter positioned between the light source and photo cell, a diaphragm having an aperture formed therein in a predetermined position and located between said filter and photo cell whereby the aperture in the diaphragm passes a well defined column of light rays from the light source to the photo cell; a hollow disc cuvette rotatably mounted in the photometer between said diaphragm and photocell for rotation in a vertical plane with its central axis in a horizontal plane, said vertical plane being located in and transverse to the path of light rays passing through the diaphragm, said cuvette containing a supply of citrated plasma to be measured; means for heating said disc cuvette to a predetermined temperature; and means for rotating said disc cuvette at a speed of between 10 and 60 revolutions per minute; said disc cuvette being located in the photometer at a position with respect to said diaphragm wherein the light rays from the diaphragm pass through a lower quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 4

A device for the photometric measuring of the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma, comprising a photometer including a light source and a photo cell aligned with the light source to receive light rays therefrom, a light filter positioned between the light source and photo cell, a diaphragm having an aperture formed therein in a predetermined position and located between said filter and photo cell whereby the aperture in the diaphragm passes a well defined column of light rays from the light source to the photo cell; a hollow disc cuvette rotatably mounted in the photometer between said diaphragm and photocell for rotation in a vertical plane with its central axis in a horizontal plane, said vertical plane being located in and transverse to the path of light rays passing through the diaphragm, said cuvette containing a supply of citrated plasma to be measured; means for heating said disc cuvette to a predetermined temperature; and means for rotating said disc cuvette at a speed of between 10 and 60 revolutions per minute; said disc cuvette being located in the photometer at a position with respect to said diaphragm wherein the light rays from the diaphragm pass through the lower right quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 5

A device for the photometric measuring of the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma, comprising a photometer including a light source and a photo cell aligned with the light source to receive light rays therefrom, a light filter positioned between the light source and photo cell, a diaphragm having an aperture formed therein in a predetermined position and located between said filter and photo cell whereby the aperture in the diaphragm passes a well defined column of light rays from the light source to the photo cell; a hollow disc cuvette rotatably mounted in the photometer between said diaphragm and photocell for rotation in a vertical plane with its central axis in a horizontal plane, said vertical plane being located in and transverse to the path of light rays passing through the diaphragm, said cuvette containing a supply of citrated plasma to be measured; means for heating said disc cuvette to a predetermined temperature; and means for rotating said disc cuvette at a speed of between 10 and 60 revolutions per minute; said disc cuvette being located in the photometer at a position with respect to said diaphragm wherein the light rays from the diaphragm pass through the lower right quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 10

The method of measuring the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma comprising the steps of placing a supply of blood platelet rich citrated plasma in a hollow transparent disc cuvette; placing said disc in a vertical plane with its central axis in a horizontal plane; heating said cuvette to a predetermined relatively stable temperature, rotating the disc cuvette containing said citrated plasma in said vertical plane about its central axis at a speed of rotation of between 10 and 60 revolutions per minute and passing a light beam transversely through said disc from a light source to a photocell along a horizontal path which is generally perpendicular to the plane in which said disc rotates; and producing a well defined beam of light from the light source and positioning the disc cuvette between the light source and photocell such that said beam of light passes through a lower quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 11

The method of measuring the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma comprising the steps of placing a supply of blood platelet rich citrated plasma in a hollow transparent disc cuvette; placing said disc in a vertical plane with its central axis in a horizontal plane; heating said cuvette to a predetermined relatively stable temperature, rotating the disc cuvette containing said citrated plasma in said vertical plane about its central axis at a speed of rotation of between 10 and 60 revolutions per minute and passing a light beam transversely through said disc from a light source to a photocell along a horizontal path which is generally perpendicular to the plane in which said disc rotates; and producing a well defined beam of light from the light source and positioning the disc cuvette between the light source and photocell such that said beam of light passes through a lower quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 12

The method of measuring the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma comprising the steps of placing a supply of blood platelet rich citrated plasma in a hollow transparent disc cuvette; placing said disc in a vertical plane with its central axis in a horizontal plane; heating said cuvette to a predetermined relatively stable temperature, rotating the disc cuvette containing said citrated plasma in said vertical plane about its central axis at a speed of rotation of between 10 and 60 revolutions per minute and passing a light beam transversely through said disc from a light source to a photocell along a horizontal path which is generally perpendicular to the plane in which said disc rotates; and including the step of producing a well defined beam of light from the light source and positioning the disc cuvette between the light source and photocell such that said beam of light passes through the lower right quadrant of the disc cuvette with the disc viewed facing the diaphragm.

Claim 13

The method of measuring the spontaneous aggregation of blood platelets in blood platelet rich citrated plasma comprising the steps of placing a supply of blood platelet rich citrated plasma in a hollow transparent disc cuvette; placing said disc in a vertical plane with its central axis in a horizontal plane; heating said cuvette to a predetermined relatively stable temperature, rotating the disc cuvette containing said citrated plasma in said vertical plane about its central axis at a speed of rotation of between 10 and 60 revolutions per minute and passing a light beam transversely through said disc from a light source to a photocell along a horizontal path which is generally perpendicular to the plane in which said disc rotates; and including the step of producing a well defined beam of light from the light source and positioning the disc cuvette between the light source and photocell such that said beam of light passes through the lower right quadrant of the disc cuvette with the disc viewed facing the diaphragm.