US4063014A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4"-O-sulfonyl erythromycin-9-O-oxime derivatives
Assignee: Abbott Laboratories
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Filing: 1975-06-12
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Granted: 1977-12-13
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Expires: 1995-06-12
Abstract
Abstract A 4"-O-sulfonyl erythromycin derivative of the following structural formula: ##STR1## where R is selected from the group consisting of oxygen, oxime, and substituted oxime, R 1 is hydrogen or hydroxy and R 2 is selected from the group consisting of phthalimide, substituted amides, benzamides, substituted benzamides, sulfonamides, substituted sulfonamides, amines, substituted amines, phenylurea, substituted phenylurea, phenylthiourea, substituted phenylthiourea, thiophenol and substituted thiophenol, phenoxides and substituted phenoxides and R 3 is hydrogen or methyl. The present sulfonyl derivatives of erythromycin A, B and C are useful as antibiotics.
Inventors
- 👤 Robert Hallas
- 👤 Jerry Roy Martin
- 👤 John Soloman Tadanier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 16:43
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
54 words
A 4"-O-sulfonyl erythromycin derivative of the following structural formula: ##STR4## wherein R is methyloxime, R 1 is hydrogen or hydroxy and R 2 is, phthalimido, alkanoylamido, nitro- or amino-substituted-benzoylamido or -benzenesulfamido, phenyl-ureido or -thioureido wherein said phenyl group may carry dimethylamino, methoxy, chloro or nitro, or CBZ-glycylamido and R 3 is hydrogen or methyl.
Claim 2
Dependent Claim
54 words
A 4"-O-sulfonyl erythromycin derivative of the following structural formula: ##STR4## wherein R is methyloxime, R 1 is hydrogen or hydroxy and R 2 is, phthalimido, alkanoylamido, nitro- or amino-substituted-benzoylamido or -benzenesulfamido, phenyl-ureido or -thioureido wherein said phenyl group may carry dimethylamino, methoxy, chloro or nitro, or CBZ-glycylamido and R 3 is hydrogen or methyl.
Claim 3
Dependent Claim
19 words
A compound according to claim 1 wherein R 1 and R 3 are hydrogen and R 2 is phthalimido.
Claim 4
Dependent Claim
22 words
A compound according to claim 1 where R 1 is hydrogen, R 3 is methyl and R 2 is a substituted phenylthiourea.
Claim 5
Dependent Claim
22 words
A compound according to claim 1 wherein R 1 is hydroxy, R 3 is methyl and R 2 is a substituted phenylthiourea.
Claim 6
Dependent Claim
22 words
A compound according to claim 1 wherein R 1 is hydrogen, R 3 is methyl and R 2 is a substituted phenylurea.
Claim 7
Dependent Claim
25 words
A compound according to claim 1 wherein R is methyloxime, R 1 is hydroxy, R 3 is methyl and R 2 is a substituted phenylurea.
References Cited (Backward Citations)
US3869445A
Cited
US3836819A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-12-12 | 1981-06-13 | 1981-12-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-12-12 | 1985-06-13 | 1985-12-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-12-12 | 1989-06-13 | 1989-12-13 | $7700.00 | Window Closed / Lapsed |