US4061538A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Enzymatically oxidizing interferon
Assignee: Sandoz AG
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Filing: 1975-02-06
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Granted: 1977-12-06
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Expires: 1995-02-06
Abstract
Abstract The invention provides structurally modified interferons, processes for producing such and a method of purification of interferons and structurally modified interferons. The modified interferons are useful as anti-viral agents.
Inventors
- 👤 Friedrich Dorner
- 👤 Marianne Scriba
- 👤 Rudolf Weil
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:57
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; C07K14/555; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S435/00; Y10S435/803; Y10S435/811; Y10S435/8215; Y10S435/822; Y10S435/842; Y10S435/911; Y10S435/913; Y10S435/917
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
27 words
A process for the production of a structurally modified interferon, comprising enzymatically oxidising the terminal galactose unit in asialointerferon with galactose oxidase and recovering the modified interferon.
Claim 2
Dependent Claim
27 words
A process for the production of a structurally modified interferon, comprising enzymatically oxidising the terminal galactose unit in asialointerferon with galactose oxidase and recovering the modified interferon.
Claim 3
Dependent Claim
20 words
A process according to claim 1, in which the oxidation is effected at a pH of from 7.0 to 8.0.
Claim 4
Dependent Claim
19 words
A process according to claim 2, in which the pH of the reaction medium is controlled with phosphate buffer.
References Cited (Backward Citations)
US3548053A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-12-05 | 1981-06-06 | 1981-12-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-12-05 | 1985-06-06 | 1985-12-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-12-05 | 1989-06-06 | 1989-12-06 | $7700.00 | Window Closed / Lapsed |