US4060598A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tablets coated with aqueous resin dispersions
Assignee: Roche Diagnostics GmbH
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Filing: 1975-10-28
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Granted: 1977-11-29
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Expires: 1995-10-28
Abstract
Abstract Coated tablets are prepared by applying to a core of active material, at least one layer of a coating composition made up of a film forming aqueous synthetic resin dispersion and from 2-50% by weight of a water or alkaline soluble material and thereafter permitting the coating composition layer to dry. The resulting coated tablet has a core surrounded by a continuous porous matrix of synthetic resin formed from the aqueous dispersion which is insoluble in water and insoluble in the gastrointestinal tract. The pores of the continuous resin matrix are filled with a discontinuous particulate material which is water or alkaline soluble. The coated tablet initially is air and moisture tight.
Inventors
- 👤 Gregor Groppenbacher
- 👤 Peter Rieckmann
- 👤 Werner Rothe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:05
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2806; A61K9/2833; A61K9/284; A61K9/2893
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
114 words
Coated tablet comprising a core of active material soluble in the gastrointestinal tract and a coating surrounding said core said coating comprising a continuous porous matrix of a synthetic resin insoluble in the gastrointestinal tract and a water or alkaline soluble material in the pores of said matrix, said coating being formed by applying to said core at least one layer of a coating composition of a film forming aqueous zynthetic resin dispersion with a resin content between 30 and 60% by weight and from 2 to 50% by weight of said water or alkaline soluble material and permitting said coating composition layer to dry, said coated tablet being initially air and moisture tight.
Claim 2
Dependent Claim
114 words
Coated tablet comprising a core of active material soluble in the gastrointestinal tract and a coating surrounding said core said coating comprising a continuous porous matrix of a synthetic resin insoluble in the gastrointestinal tract and a water or alkaline soluble material in the pores of said matrix, said coating being formed by applying to said core at least one layer of a coating composition of a film forming aqueous zynthetic resin dispersion with a resin content between 30 and 60% by weight and from 2 to 50% by weight of said water or alkaline soluble material and permitting said coating composition layer to dry, said coated tablet being initially air and moisture tight.
Claim 3
Dependent Claim
26 words
Coated tablet of claim 1 wherein said water soluble material is selected from the group consisting of salt, sugar, polyethylene glycol, polyvinyl pyrrolidone and starch syrup.
Claim 4
Dependent Claim
15 words
Coated tablet of claim 1 wherein said alkaline soluble material is a higher fatty acid.
Claim 5
Dependent Claim
13 words
Coated tablet of claim 1 wherein said alkaline soluble material is lauric acid.
Claim 6
Dependent Claim
30 words
Coated tablet of claim 1 wherein said synthetic resin is a member selected from the group consisting of polyvinyl ester, polyvinyl acetal, polyvinyl chloride, butadiene-styrene copolymer and polyacrylic acid ester.
Claim 7
Dependent Claim
10 words
Coated tablet of claim 1 additionally containing an insoluble filler.
Claim 8
Dependent Claim
27 words
Coated tablet of claim 1 wherein said insoluble filler is present in an amount of up to 50% referred to the amount of aqueous synthetic resin dispersion.
Claim 9
Dependent Claim
30 words
Coated tablet of claim 6 wherein said insoluble filler is a member selected from the group consisting of talc, chalk, kaolin, maize starch, rich starch and highly dispersed silicic acid.
Claim 10
Dependent Claim
22 words
Coated tablet of claim 1 additionally containing at least one member selected from the group consisting of dye stuffs and colored pigments.
Claim 11
Dependent Claim
21 words
Coated tablet of claim 1 additionally containing at least one member selected from the group consisting of flavoring agents and perservatives.
Claim 12
Dependent Claim
9 words
Coated tablet of claim 1 additionally containing a plasticizer.
Claim 13
Dependent Claim
13 words
Coated tablet of claim 11 wherein said plasticizer is a phthalic acid ester.
Claim 14
Dependent Claim
41 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous polyvinyl acetate dispersion, 13 parts of talc, 1 part of polyethylene glycol (average molecular weight 20,000) 1 part of tartrazin and 70 parts demineralized water.
Claim 15
Dependent Claim
44 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous polyvinyl acetate dispersion, 6 parts of talc, 6 parts of saccharose, 3 parts polyethylene glycol (average molecular weight 20,000), 1 part of tartrazin and 90 parts demineralized water.
Claim 16
Dependent Claim
48 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous polyvinyl propionate dispersion, 100 parts talc, 25 parts polyethylene glycol (average molecular weight 20,000) 0.5 parts sodium lauryl sulfate, 2 parts of titanium dioxide, 1 part tartrazin and 170 parts demineralized water.
Claim 17
Dependent Claim
39 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous polyvinyl chloride dispersion, 15 parts chalk, 8 parts saccharose, 0.5 parts sodium lauryl sulfate, 10 parts titanium dioxide and 60 parts demineralized water.
Claim 18
Dependent Claim
45 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous dispersion of polyacrylic acid ester, 20 parts maize starch, 5 parts polyethylene glycol, 5 parts polyvinyl alcohol, 3 parts titanium dioxide, 1 part Ponceau-6R and 90 parts demineralized water.
Claim 19
Dependent Claim
44 words
Coated tablet of claim 1 wherein said coating comprises 200 parts of an approximately 50% aqueous dispersion of a butadiene-styrene copolymer, 20 parts talc, 30 parts chalk, 7 parts saccharose, 20 parts polyvinyl pyroolidone, 10 parts ferric oxide pigment and 120 parts demineralized water.
Claim 20
Dependent Claim
18 words
Coated tablet of claim 1 wherein said coating comprises a 30 to 50% aqueous, plasticizer-free acrylic resin dispersion.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-28 | 1981-05-30 | 1981-11-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-28 | 1985-05-30 | 1985-11-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-28 | 1989-05-30 | 1989-11-29 | $7700.00 | Window Closed / Lapsed |