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US4059762A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and apparatus for determining accuracy of radiation measurements made in the presence of background radiation

Assignee: Beckman Coulter Inc
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Filing: 1976-05-17
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Granted: 1977-11-22
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Expires: 1996-05-17
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Abstract

Abstract A radioactivity measuring instrument, and a method related to its use, for determining the radioactivity of a sample measured in the presence of significant background radiation, and for determining an error value relating to a specific probability of accuracy of the result. Error values relating to the measurement of background radiation alone, and to the measurement of sample radiation and background radiation together, are combined to produce a true error value relating to the sample radiation alone.

Inventors

  • 👤 Donald L. Horrocks

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 16:40
CPC Classifications
G; G01; G01T; G01T1/00; G01T1/16; G01T1/17; G01T1/178

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 101 words
A method of determining the accuracy of a measurement of radioactivity of a sample alone when taken in the presence of background radiation, said method comprising the steps of: measuring the background radiation alone; measuring radiation from the sample in the presence of said background radiation; determining error values respectively related to said measuring steps; determining the radiation attributable to the sample alone, by subtracting the result of said first-mentioned measuring step from the result of said second-mentioned measuring step; and determining the accuracy of the result of said last-mentioned step by combining the error values related to said measuring steps.
Claim 2
Independent Claim 101 words
A method of determining the accuracy of a measurement of radioactivity of a sample alone when taken in the presence of background radiation, said method comprising the steps of: measuring the background radiation alone; measuring radiation from the sample in the presence of said background radiation; determining error values respectively related to said measuring steps; determining the radiation attributable to the sample alone, by subtracting the result of said first-mentioned measuring step from the result of said second-mentioned measuring step; and determining the accuracy of the result of said last-mentioned step by combining the error values related to said measuring steps.
Claim 3
Dependent Claim 64 words
A method as set forth in claim 1, wherein: said determining steps are performed from time to time during said second-mentioned measuring step; and said method further includes the steps of comparing the determined error value of the determined radiation of the sample with a desired error value, and terminating said second-mentioned measuring step when the determined error value reaches the desired error value.
Claim 4
Dependent Claim 41 words
A method as set forth in claim 1, and further including the step of storing the measured value of background radiation and the associated error value, for subsequent use by said steps of determining sample radiation and its associated error value.
Claim 5
Independent Claim 151 words
A method of determining an error value ±E s relating to a particular probability of accuracy of a measurement of radioactivity of a sample taken in the presence of background radiation, said method comprising the steps of: measuring the background radiation R b alone; measuring radiation R s+b from the sample in the presence of the background radiation; determining error values ±E b and ±E s+b relating to the respective results of said measuring steps, there being a particular probability that the true values of radiation measured in said measuring steps fall within the ranges R b ± E b and R s+b ± E s+b , respectively; determining the radiation R s attributable to the sample alone by substracting R b from R s+b ; and determining the error value ±E s relating to the value of R s by combining the values of ±E b and +E s ±b.
Claim 6
Independent Claim 151 words
A method of determining an error value ±E s relating to a particular probability of accuracy of a measurement of radioactivity of a sample taken in the presence of background radiation, said method comprising the steps of: measuring the background radiation R b alone; measuring radiation R s+b from the sample in the presence of the background radiation; determining error values ±E b and ±E s+b relating to the respective results of said measuring steps, there being a particular probability that the true values of radiation measured in said measuring steps fall within the ranges R b ± E b and R s+b ± E s+b , respectively; determining the radiation R s attributable to the sample alone by substracting R b from R s+b ; and determining the error value ±E s relating to the value of R s by combining the values of ±E b and +E s ±b.
Claim 7
Dependent Claim 34 words
A method as set forth in claim 4, wherein said step of determining the error value ±E s is performed in accordance with the expression: ±E.sub.s = ± √ (E.sub.b) .sup.2 + (E.sub.s+b) .sup.2.
Claim 8
Dependent Claim 68 words
A method as set forth in claim 4, wherein: said determining steps are performed from time to time during said step of measuring R s+b ; and said method further includes the steps of comparing the determined error value ±E s with a desired error value, and terminating said step of measuring R s+b when the magnitude of the error value ±E s reaches the desired error value.
Claim 9
Dependent Claim 183 words
Apparatus for determining the accuracy of a measurement of radioactivity of a sample taken in the presence of background radiation, said apparatus comprising: radioactivity event counting means for accumulating counts of radioactive events detected as being attributable to background radiation alone and for accumulating counts attributable to the sample taken together with the background radiation; dividing circuit means for providing a signal indicative of the time rate of accumulation of counts by said event counting means; error value calculation circuit means for determining an error value relating to a particular probability of accuracy of the values of rate of accumulation of counts; subtraction circuit means for subtracting a signal indicative of a radiation rate from the background from signal indicative of a radiation rate from the sample and background together, to obtain a radiation rate attributable to the sample alone; and error value correction circuit means, for combining error values relating to the rates of radiation from the background alone and from the background and sample together, and for thereby generating an error value relating to the radiation rate of the sample alone.
Claim 10
Dependent Claim 183 words
Apparatus for determining the accuracy of a measurement of radioactivity of a sample taken in the presence of background radiation, said apparatus comprising: radioactivity event counting means for accumulating counts of radioactive events detected as being attributable to background radiation alone and for accumulating counts attributable to the sample taken together with the background radiation; dividing circuit means for providing a signal indicative of the time rate of accumulation of counts by said event counting means; error value calculation circuit means for determining an error value relating to a particular probability of accuracy of the values of rate of accumulation of counts; subtraction circuit means for subtracting a signal indicative of a radiation rate from the background from signal indicative of a radiation rate from the sample and background together, to obtain a radiation rate attributable to the sample alone; and error value correction circuit means, for combining error values relating to the rates of radiation from the background alone and from the background and sample together, and for thereby generating an error value relating to the radiation rate of the sample alone.
Claim 11
Dependent Claim 38 words
Apparatus as set forth in claim 7, and further including display means for visually displaying values of the radiation rate attributable to the sample alone, and its associated error value determined in said error value correction circuit means.
Claim 12
Dependent Claim 59 words
Apparatus as set forth in claim 7, and further including: comparator means for comparing error values determined from time to time by said error value correction circuit means with a desired error value; and means for terminating operation of said event counting means when said comparator means detects that the determined error value has reached the desired error value.
Claim 13
Dependent Claim 66 words
Apparatus as set forth in claim 7, wherein: the error values relating to the radiation rates from the background alone and the background and sample together are ±E b and ±E s+b , respectively; and the error value determined by said error value correction circuit means is given by the expression ±E s = ± √ (E b ) 2 + (E s+b ) 2 .

References Cited (Backward Citations)

US3510655A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-11-21 1981-05-23 1981-11-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-11-21 1985-05-23 1985-11-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-11-21 1989-05-23 1989-11-22 $7700.00 Window Closed / Lapsed

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