US4059687A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ester substituted dibiguanides and non-toxic antimicrobial compositions thereof
Assignee: Colgate Palmolive Co
•
Filing: 1976-11-26
•
Granted: 1977-11-22
•
Expires: 1996-11-26
Abstract
Abstract Novel dibiguanides containing an ester substituent on the terminal phenyl radical and free of the presence of, or the tendency to form, toxic substances; the process of preparing said dibiguanides, and compositions containing an effective antimicrobial amount of said dibiguanides admixed with a pharmaceutical carrier.
Inventors
- 👤 Robert Andrew Bauman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 20:26
CPC Classifications
A; A01; A01N; A01N47/00; A01N47/40; A01N47/42; A01N47/44; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/43; A61Q; A61Q11/00; C; C07; C07C; C07C279/00; C07C279/20; C07C279/24; C07C279/26; C07C279/265
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
83 words
A dibiguanide compound free of toxic substances having the structural formula: ##STR7## wherein one of A and B is hydrogen and the other is the ester radical ##STR8## and R is an alkyl group containing 1-8 carbon atoms and n is an integer from 5 to 12; and the acid salts thereof selected from the group consisting of HCl, HBr, HI, HF, H 2 SO 4 , CH 3 COOH, gluconic acid, H 2 PO 3 F and H 3 PO 4 .
Claim 2
Dependent Claim
83 words
A dibiguanide compound free of toxic substances having the structural formula: ##STR7## wherein one of A and B is hydrogen and the other is the ester radical ##STR8## and R is an alkyl group containing 1-8 carbon atoms and n is an integer from 5 to 12; and the acid salts thereof selected from the group consisting of HCl, HBr, HI, HF, H 2 SO 4 , CH 3 COOH, gluconic acid, H 2 PO 3 F and H 3 PO 4 .
Claim 3
Dependent Claim
11 words
A compound in accordance with claim 1 wherein n is 6.
Claim 4
Dependent Claim
17 words
A compound in accordance with claim 1 wherein A is an ester radical and B is hydrogen.
Claim 5
Dependent Claim
17 words
A compound in accordance with claim 1 wherein B is an ester radical and A is hydrogen.
Claim 6
Dependent Claim
12 words
A compound in accordance with claim 1 having the formula N,N"-bis(4-butyloxycarbonylphenyl)-3,12,diimino-2,4,11,13-tetraazatetradecanediimidamide dihydrochloride.
Claim 7
Dependent Claim
11 words
A compound in accordance with claim 1 having the formula N,N"-bis(4-pentyloxycarbonylphenyl)-3,12,diimino-2,4,11,13,-tetraazatetradecanediimidamide.
Claim 8
Dependent Claim
13 words
A compound in accordance with claim 1, having the formula N,N"-bis(4-butyloxycarbonylphenyl)-3, 12-diimino-2,4,11,13-tetraazatetradecanediimidamide diacetate.
Claim 9
Dependent Claim
20 words
A non-toxic composition containing an effective antimicrobial amount of the compound defined in claim 1 admixed with a pharmaceutical carrier.
Claim 10
Dependent Claim
20 words
A non-toxic composition containing an effective antimicrobial amount of the compound defined in claim 1 admixed with an oral preparation.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-21 | 1981-05-23 | 1981-11-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-21 | 1985-05-23 | 1985-11-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-21 | 1989-05-23 | 1989-11-22 | $7700.00 | Window Closed / Lapsed |