US4059686A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical preparation for oral cavity administration
Assignee: Nippon Kayaku Co Ltd
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Filing: 1975-09-22
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Granted: 1977-11-22
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Expires: 1995-09-22
Abstract
Abstract A pharmaceutical preparation of oral cavity administration, characterized by being a mixture of a pharmacologically active agent, a pharmaceutical carrier, and sodium polyacrylate, in conventional dosage form. It has advantages in that it adheres strongly to local site and dissolves gradually over a prolonged period of time while releasing appropriate amounts of the active agent.
Inventors
- 👤 Wataru Tanaka
- 👤 Eiichiro Akito
- 👤 Koichi Yoshida
- 👤 Takashi Terada
- 👤 Hiroshi Ninomiya
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:36
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/30; A61K47/32; A61K9/00; A61K9/0012; A61K9/0053; A61K9/006; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2027
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
46 words
A pharmaceutical preparation for oral cavity administration comprising 10 to 60% by weight of sodium polyacrylate, 90 to 10% by weight of a pharmaceutical carrier selected from the group consisting of an excipient and ointment, and 50 to 0.05% by weight of a pharmacologically active agent.
Claim 2
Dependent Claim
46 words
A pharmaceutical preparation for oral cavity administration comprising 10 to 60% by weight of sodium polyacrylate, 90 to 10% by weight of a pharmaceutical carrier selected from the group consisting of an excipient and ointment, and 50 to 0.05% by weight of a pharmacologically active agent.
Claim 3
Dependent Claim
24 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the sodium polyacrylate has an average molecular weight of 185,000 to 8,500,000.
Claim 4
Dependent Claim
32 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the excipient is microcrystalline cellulose, mannitol, crystalline lactose, spray-dried lactose, sorbitol, anhydrous calcium phosphate, amylose, powdered lactose, or powdered sucrose.
Claim 5
Dependent Claim
41 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the ointment base is white petrolatum, polyethylene glycol, a compatible mixture of peanut oil or purified sesame oil with beeswax, or a compatible mixture of polyethylene and liquid paraffin.
Claim 6
Dependent Claim
49 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the pharmacologically active agent is selected from the group consisting of a steroid hormone, an antiinflammatory steroid, an antiinflammatory enzyme, callicrein, a peptide, a nitrate ester, isoproterenol, methacholine, an antibiotic, a lysozyme, dextrinase, and a local anesthetic.
Claim 7
Dependent Claim
31 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the said pharmaceutical is selected from the group consisting of a buccal tablet, a sublingual tablet, and an ointment.
Claim 8
Dependent Claim
59 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the pharmaceutical preparation comprising 10 to 60% by weight of sodium polyacrylate, 80 to 10% by weight of an excipient and 50 to 0.05% by weight of a pharmacologically active agent is a tablet selected from the group consisting of a buccal tablet and a sublingual tablet.
Claim 9
Dependent Claim
47 words
A pharmaceutical preparation for oral cavity administration according to claim 1, wherein the pharmaceutical preparation comprising 10 to 50% by weight of sodium polyacrylate, 90 to 40% by weight of an ointment base, and 10 to 0.05% by weight of a pharmacologically active agent is an ointment.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-21 | 1981-05-23 | 1981-11-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-21 | 1985-05-23 | 1985-11-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-21 | 1989-05-23 | 1989-11-22 | $7700.00 | Window Closed / Lapsed |