US4052513A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stable topical anesthetic compositions
Assignee: Bayer Consumer Care Holdings LLC
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Filing: 1976-04-02
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Granted: 1977-10-04
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Expires: 1996-04-02
Abstract
Abstract A cosmetically elegant and stable oil in water emulsion for use as a topical anesthetic containing 0.5-15% benzocaine solubilized in water with a dialkyl ester of an alkanedioic acid having the formula ROOC--C n H 2n --C00R' where R and R' are alkyl groups of from 1 to 4 carbon atoms and n is an integer from 1 to 8.
Inventors
- 👤 Carl Kaplan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 02:40
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/06; A61K47/08; A61K47/14; A61K8/00; A61K8/02; A61K8/04; A61K8/06; A61K8/062; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/40; A61K8/44; A61K8/445; A61Q; A61Q19/00; A61Q19/004
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
81 words
A stable cosmetically elegant oil in water emulsion useful as a topical anesthetic comprising 0.5 to 15 percent of benzocaine; 5 to 40 percent of a cosmetically acceptable dialkyl ester of an alkanedioic acid which is a liquid at 10° C and having the formula ROOC--C n H 2n --COOR', where R and R' are alkyl groups of from 1 to 4 carbon atoms and n is an integer from 1 to 8; at least one cosmetically acceptable surfactant, and water.
Claim 2
Dependent Claim
81 words
A stable cosmetically elegant oil in water emulsion useful as a topical anesthetic comprising 0.5 to 15 percent of benzocaine; 5 to 40 percent of a cosmetically acceptable dialkyl ester of an alkanedioic acid which is a liquid at 10° C and having the formula ROOC--C n H 2n --COOR', where R and R' are alkyl groups of from 1 to 4 carbon atoms and n is an integer from 1 to 8; at least one cosmetically acceptable surfactant, and water.
Claim 3
Dependent Claim
17 words
A composition according to claim 1 wherein C n H 2n is a straight chained alkyl group.
Claim 4
Dependent Claim
12 words
A composition according to claim 2 wherein said ester is diethyl sebacate.
Claim 5
Dependent Claim
12 words
A composition according to claim 2 wherein said ester is diisopropyl adipate.
Claim 6
Dependent Claim
29 words
A composition according to claim 4 wherein the benzocaine concentration is from about 5 to 10 percent and the diisopropyl adipate concentration is from about 15 to 30 percent.
Claim 7
Dependent Claim
15 words
A composition according to claim 1 wherein the benzocaine concentration is at least 5 percent.
Claim 8
Dependent Claim
13 words
A composition according to claim 1 wherein said surfactant comprises a nonionic surfactant.
Claim 9
Dependent Claim
22 words
A composition according to claim 7 wherein the concentration of said nonionic surfactant is in the range of 5 to 20 percent.
Claim 10
Dependent Claim
21 words
A composition according to claim 8 wherein the concentration of said water is in the range of 30 to 90 percent.
Claim 11
Dependent Claim
23 words
A method of alleviating minor pain of irritated skin comprising the step of applying the composition of claim 1 to the irritated skin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-10-03 | 1981-04-04 | 1981-10-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-10-03 | 1985-04-04 | 1985-10-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-10-03 | 1989-04-04 | 1989-10-04 | $7700.00 | Window Closed / Lapsed |