US4049794A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of infections in animals
Assignee: Bayer AG
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Filing: 1976-03-05
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Granted: 1977-09-20
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Expires: 1996-03-05
Abstract
Abstract There is disclosed novel non-antigenic attenuated viruses which non-specifically stimulate the natural defense mechanism of a host organism with a detectable non-specific induction of interferon; to methods for their production and to their use for the prophylaxis and treatment of viral and bacterial infections in human and veterinary medicine. The aforesaid term "non-antigenic attenuated virus" in this application means "an attenuated virus being incapable to cause an immunological cross-reaction with the original virus".
Inventors
- 👤 Otto-Christian Straub
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 06:57
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/66; A61K35/76; A61K35/766; A61K35/12; A61K2035/126; C; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16732
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
110 words
A method for prophylaxis and treatment of respiratory and genital infections in animals which comprises administering to the animals an attenuated virus capable of stimulating the natural defense mechanism of a host animal with a detectable non-specific induction of interferon without antigenic effect, wherein said attenuated virus is produced by passing a virus through a plurality of at least 300 tissue cultures to achieve a degree of attenuation such that antigenic effect cannot be detected in the presence of a detectable non-specific induction of interferon in said host animal, and wherein said virus is AUJESZKY/pseudo-rabies virus, AUJESZKY/ pseudo-rabies virus--strain S/T, Influenza virus Al, Influenza virus Al--strain FM1 or IPV virus.
Claim 2
Independent Claim
110 words
A method for prophylaxis and treatment of respiratory and genital infections in animals which comprises administering to the animals an attenuated virus capable of stimulating the natural defense mechanism of a host animal with a detectable non-specific induction of interferon without antigenic effect, wherein said attenuated virus is produced by passing a virus through a plurality of at least 300 tissue cultures to achieve a degree of attenuation such that antigenic effect cannot be detected in the presence of a detectable non-specific induction of interferon in said host animal, and wherein said virus is AUJESZKY/pseudo-rabies virus, AUJESZKY/ pseudo-rabies virus--strain S/T, Influenza virus Al, Influenza virus Al--strain FM1 or IPV virus.
Claim 3
Dependent Claim
11 words
The method of claim 1 in which the animals are cattle.
Claim 4
Dependent Claim
11 words
The method of claim 1 in which the animals are pigs.
Claim 5
Dependent Claim
21 words
The method of claim 1 in which the virus is applied as a spray to a mucuous membrane of the animal.
Claim 6
Dependent Claim
15 words
The method of claim 1 in which the virus is applied to the animal intramuscularly.
References Cited (Backward Citations)
US3674864A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-19 | 1981-03-21 | 1981-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-19 | 1985-03-21 | 1985-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-19 | 1989-03-21 | 1989-09-20 | $7700.00 | Window Closed / Lapsed |