US4049702A
Expired / Lapsed
US
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γ-Glutamyl-4-nitroanilide compounds
Assignee: Roche Diagnostics GmbH
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Filing: 1975-06-23
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Granted: 1977-09-20
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Expires: 1995-06-23
Abstract
Abstract gamma -Glutamyl-4-nitroanilide compounds of the formula <IMAGE> wherein R is a gamma -glutamyl radical and X is an acid group, and salts of such compounds, are used to determine gamma -glutamyl-transpeptidase by contacting a sample suspected of containing gamma -glutamyltranspeptidase with said compound and glycylglycine and determining the liberation of the resulting p-nitro-aniline compound as a measure of the gamma -glutamyltranspeptidase activity initially present in the sample.
Inventors
- 👤 Erich Bernt
- 👤 Wolfgang Gruber
- 👤 Erich Haid
- 👤 Fritz Stahler
- 👤 August Wilhelm Wahlefeld
- 👤 Gunter Weimann
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:47
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/48
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
33 words
γ-Glutamyl-4-nitroanilide compound of the formula ##STR8## wherein R is a γ-glutamyl radical and X is a sulfonic acid group or a thiosulfonic acid group and alkali, alkaline earth, ammonium and amine salts thereof.
Claim 2
Dependent Claim
33 words
γ-Glutamyl-4-nitroanilide compound of the formula ##STR8## wherein R is a γ-glutamyl radical and X is a sulfonic acid group or a thiosulfonic acid group and alkali, alkaline earth, ammonium and amine salts thereof.
Claim 3
Dependent Claim
14 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, wherein X is a sulfonic acid group.
Claim 4
Dependent Claim
14 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, wherein X is a thiosulfonic acid group.
Claim 5
Dependent Claim
12 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its ammonium salt form.
Claim 6
Dependent Claim
13 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its alkali metal salt form.
Claim 7
Dependent Claim
14 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its alkaline earth metal salt form.
Claim 8
Dependent Claim
12 words
γ-Glutamyl-4-nitroanilide compound as claimed in claim 1, in its amine salt form.
References Cited (Backward Citations)
US2221131A
Cited
US2951090A
Cited
US3703441A
Cited
US3739013A
Cited
US3732290A
Cited
US3803223A
Cited
US3773626A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-19 | 1981-03-21 | 1981-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-19 | 1985-03-21 | 1985-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-19 | 1989-03-21 | 1989-09-20 | $7700.00 | Window Closed / Lapsed |