US4046918A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of cells
Assignee: Fundacion de Estudios Farmaco-Biologicos
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Filing: 1975-01-24
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Granted: 1977-09-06
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Expires: 1995-01-24
Abstract
Abstract Method of treating virus disorders by administering 1,2-diphenyl-α,β-diketone into the blood. Entry of this compound into the sick cells results in, because of the pH and redox-potential conditions in those cells, oxidation phenomena and deposition of an antiseptic substance in the sick cells, thereby causing cellular aging and necrosis.
Inventors
- 👤 Gregorio Ramon Cebrian
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 08:19
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/365; A61K31/12
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
39 words
A method for selective cell necrosis, which comprises administering through the circulatory system to the altered cells of a patient having such altered cells a pharmaceutically effective amount of a composition containing 1,2-diphenyl-α,β-diketone and a pharmaceutically suitable carrier therefor.
Claim 2
Independent Claim
39 words
A method for selective cell necrosis, which comprises administering through the circulatory system to the altered cells of a patient having such altered cells a pharmaceutically effective amount of a composition containing 1,2-diphenyl-α,β-diketone and a pharmaceutically suitable carrier therefor.
Claim 3
Dependent Claim
64 words
The method according to claim 1, wherein the administration is perorally and the composition is prepared by mixing an oil or ethyl oleate, with a low degree of acidity, and 1,2-diphenyl-α ,β-diketone under stirring at a temperature between ambient temperature and 80° C., to dissolve the mixture, the proportion of 1,2-diphenyl-α,β-diketone being between 1 and 4% w/v, and allowing the resultant mixture to cool.
Claim 4
Independent Claim
41 words
A method for selective cell necrosis, which comprises administering into the blood of a patient affected with altered cells, a pharmaceutically effective amount of 1,2-diphenyl-α,β-diketone in the form of a solution in a pharmaceutically acceptable liposoluble medium suitable for internal administration.
Claim 5
Independent Claim
41 words
A method for selective cell necrosis, which comprises administering into the blood of a patient affected with altered cells, a pharmaceutically effective amount of 1,2-diphenyl-α,β-diketone in the form of a solution in a pharmaceutically acceptable liposoluble medium suitable for internal administration.
Claim 6
Dependent Claim
21 words
A composition for achieving selective cell necrosis, comprising 1,2-diphenyl-α,β-diketone and a pharmaceutically acceptable liposoluble medium, as carrier, suitable for internal administration.
Claim 7
Dependent Claim
21 words
A composition for achieving selective cell necrosis, comprising 1,2-diphenyl-α,β-diketone and a pharmaceutically acceptable liposoluble medium, as carrier, suitable for internal administration.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-05 | 1981-03-07 | 1981-09-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-05 | 1985-03-07 | 1985-09-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-05 | 1989-03-07 | 1989-09-06 | $7700.00 | Window Closed / Lapsed |