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US4046514A Expired / Lapsed US ⏱️ 0.0 years remaining

Test device and method for determining a component in a sample

Assignee: Bayer Corp
•
Filing: 1976-11-24
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Granted: 1977-09-06
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Expires: 1996-11-24
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Abstract

Abstract A test device and method for determining the presence of a component in a sample are disclosed, as well as a method for making the device. The device utilizes a reactant system which produces a detectable response upon contact with the sample component, the reactant system being incorporated with a carrier matrix. The carrier matrix comprises separate filaments formed into a cloth. At least one ingredient of the reactant system is incorporated with some of the filaments prior to their being formed into the cloth. The method for making the device comprises interweaving the filaments bearing at least one reactant ingredient into a warp of other filaments, knitting the filaments into a cloth, forming a mat cloth of randomly oriented filaments or affixing the filaments to a matrix support member in a substantially parallel orientation.

Inventors

  • 👤 Katharine Gentry Johnston
  • 👤 Melvin Dee Smith

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:19
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; Y; Y10; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444; Y10T436/145555; Y10T436/146666; Y10T436/17; Y10T436/173076; Y10T436/20; Y10T436/200833

Claims Analysis

Total Claims: 34
Claim 1
Independent Claim 82 words
In a test device for determining a component in a sample, wherein a carrier matrix is incorporated with a reactant system comprising at least one ingredient, said reactant system being capable of producing a detectable response upon contact with said sample component, the improvement in which said matrix is a cloth comprising longitudinal and transverse filaments, at least an effective number of said transverse filaments being the only filaments in the matrix incorporated with at least one of said reactant system ingredients.
Claim 2
Dependent Claim 82 words
In a test device for determining a component in a sample, wherein a carrier matrix is incorporated with a reactant system comprising at least one ingredient, said reactant system being capable of producing a detectable response upon contact with said sample component, the improvement in which said matrix is a cloth comprising longitudinal and transverse filaments, at least an effective number of said transverse filaments being the only filaments in the matrix incorporated with at least one of said reactant system ingredients.
Claim 3
Dependent Claim 50 words
The improvement of claim 1 in which said reactant system comprises at least two ingredients, and said effective number of transverse filaments comprises a first plurality of filaments incorporated with at least one of said ingredients and a second plurality of filaments incorporated with at least another of said ingredients.
Claim 4
Dependent Claim 40 words
The improvement of claim 1 in which at least two of said carrier matrices are provided, each of which is incorporated with a reactant system capable of producing a detectable response to a different threshold concentration of said sample component.
Claim 5
Dependent Claim 14 words
The improvement of claim 1 in which said longitudinal and transverse filaments are interwoven.
Claim 6
Dependent Claim 20 words
The improvement of claim 4 in which said longitudinal filaments are the warp and said transverse filaments are the weft.
Claim 7
Dependent Claim 20 words
The improvement of claim 4 in which said longitudinal filaments are the weft and said transverse filaments are the warp.
Claim 8
Dependent Claim 36 words
The improvement of claim 5 in which at least two of said matrices are provided, each capable of producing a detectable response to a different threshold concentration of said component, said matrices having common warp filaments.
Claim 9
Dependent Claim 36 words
The improvement of claim 6 in which at least two of said matrices are provided, each capable of producing a detectable response to a different threshold concentration of said component, said matrices having common weft filaments.
Claim 10
Dependent Claim 33 words
The improvement of claim 1 wherein said effective number of transverse filaments present in said matrix defines at least one numerical or geometrical indicium corresponding to a predetermined threshold concentration of said component.
Claim 11
Dependent Claim 17 words
The improvement of claim 9 wherein said effective number of filaments defines at least one arabic numeral.
Claim 12
Dependent Claim 14 words
The improvement of claim 10 wherein said numeral corresponds directly to said threshold concentration.
Claim 13
Dependent Claim 18 words
The improvement of claim 9 wherein said effective number of transverse filaments define at least one geometrical indicium.
Claim 14
Dependent Claim 81 words
In a test device for determining a component in a sample, wherein a carrier matrix is incorporated with a reactant system comprising at least one ingredient, said reactant system being capable of producing a detectable response upon contact with said sample component, the improvement in which said matrix is a cloth comprising a plurality of filaments at least an effective number of which having been incorporated with at least one ingredient of said reactant system prior to formation of said cloth.
Claim 15
Dependent Claim 81 words
In a test device for determining a component in a sample, wherein a carrier matrix is incorporated with a reactant system comprising at least one ingredient, said reactant system being capable of producing a detectable response upon contact with said sample component, the improvement in which said matrix is a cloth comprising a plurality of filaments at least an effective number of which having been incorporated with at least one ingredient of said reactant system prior to formation of said cloth.
Claim 16
Dependent Claim 20 words
The improvement of claim 13 in which said filaments are substantially parallel and are affixed to a matrix support member.
Claim 17
Dependent Claim 11 words
The improvement of claim 13 in which said matrix is knitted.
Claim 18
Dependent Claim 16 words
The improvement of claim 13 in which said matrix comprises a random orientation of said filaments.
Claim 19
Dependent Claim 67 words
A test device for determining a component in a test sample wherein a carrier matrix is incorporated with a reactant system which interacts with said component to produce a detectable response, the matrix comprising first and second pluralities of knitted filaments, at least an effective number of said first plurality being the only filaments in the matrix incorporated with at least one ingredient of said reactant system.
Claim 20
Dependent Claim 67 words
A test device for determining a component in a test sample wherein a carrier matrix is incorporated with a reactant system which interacts with said component to produce a detectable response, the matrix comprising first and second pluralities of knitted filaments, at least an effective number of said first plurality being the only filaments in the matrix incorporated with at least one ingredient of said reactant system.
Claim 21
Dependent Claim 23 words
The test device of claim 1 in which said component is glucose, bilirubin, urobilinogen, albumin, ketone, occult blood, nitrite, hydrogen ion, or cholesterol.
Claim 22
Dependent Claim 23 words
The test device of claim 13 in which said component is glucose, bilirubin, urobilinogen, albumin, ketone, occult blood, nitrite, hydrogen ion, or cholesterol.
Claim 23
Dependent Claim 23 words
The test device of claim 17 in which said component is glucose, bilirubin, urobilinogen, albumin, ketone, occult blood, nitrite, hydrogen ion, or cholesterol.
Claim 24
Dependent Claim 74 words
In a method for preparing a test device for determining the presence of a component in a sample wherein a cloth carrier matrix is incorporated with a reactant system capable of interacting with said component to produce a detectable response, the improvement which comprises incorporating at least one ingredient of said reactant system with at least one first filament, and forming a cloth matrix comprising said first filament and a plurality of second filaments.
Claim 25
Dependent Claim 74 words
In a method for preparing a test device for determining the presence of a component in a sample wherein a cloth carrier matrix is incorporated with a reactant system capable of interacting with said component to produce a detectable response, the improvement which comprises incorporating at least one ingredient of said reactant system with at least one first filament, and forming a cloth matrix comprising said first filament and a plurality of second filaments.
Claim 26
Dependent Claim 15 words
The improved method of claim 21 in which said cloth matrix is formed by weaving.
Claim 27
Dependent Claim 15 words
The improved method of claim 21 in which said cloth matrix is formed by knitting.
Claim 28
Dependent Claim 33 words
The improved method of claim 21 in which said cloth matrix is formed by stressing a random orientation of said first and second filaments to produce a cloth matrix of randomly oriented filaments.
Claim 29
Dependent Claim 20 words
The improved method of claim 21 in which said cloth matrix is incorporated with remaining ingredients of said reactant system.
Claim 30
Independent Claim 81 words
A method for preparing a test device for determining the presence of a component in a sample wherein a cloth carrier matrix is incorporated with a reactant system capable of interacting with said component to produce a detectable response, said method comprising incorporating at least one ingredient of said reactant system with a plurality of first filaments, incorporating remaining ingredients of said reactant system with a plurality of second filaments, and forming a cloth matrix from said first and second filaments.
Claim 31
Independent Claim 81 words
A method for preparing a test device for determining the presence of a component in a sample wherein a cloth carrier matrix is incorporated with a reactant system capable of interacting with said component to produce a detectable response, said method comprising incorporating at least one ingredient of said reactant system with a plurality of first filaments, incorporating remaining ingredients of said reactant system with a plurality of second filaments, and forming a cloth matrix from said first and second filaments.
Claim 32
Dependent Claim 14 words
The method of claim 26 in which said cloth matrix is formed by weaving.
Claim 33
Dependent Claim 14 words
The method of claim 26 in which said cloth matrix is formed by knitting.
Claim 34
Dependent Claim 32 words
The method of claim 26 in which said cloth matrix is formed by stressing a random orientation of said first and second filaments to produce a cloth matrix of randomly oriented filaments.

References Cited (Backward Citations)

US3552928A Cited
US3802842A Cited
US3785930A Cited
US3846247A Cited
US3964871A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-09-05 1981-03-07 1981-09-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-09-05 1985-03-07 1985-09-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-09-05 1989-03-07 1989-09-06 $7700.00 Window Closed / Lapsed

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