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US4045487A Expired / Lapsed US ⏱️ 0.0 years remaining

1-Dimethylamino-2,4-diphenyl-1-butene-3,4-dione

Assignee: Hoffmann La Roche Inc
•
Filing: 1976-03-18
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Granted: 1977-08-30
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Expires: 1996-03-18
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Abstract

Abstract Compounds of the formula I <IMAGE> wherein R1 is lower alkyl or phenyl lower alkyl; R2 is phenyl or substituted phenyl; and R3 is substituted or unsubstituted phenyl, naphthyl or indolyl; ARE FLUOROGENIC REAGENTS WHICH REACT WITH PRIMARY AMINO GROUPS TO FORM FLUOROPHORS. The above compounds are useful for fluorescent labeling of materials of biological importance.

Inventors

  • 👤 Roy Cleeland, Jr.
  • 👤 Emanuel Grunberg
  • 👤 Willy Leimgruber
  • 👤 Manfred Weigele

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 22:07
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/533; C; C07; C07C; C07C45/00; C07C45/56; C07C45/57; C07C45/58; C07D; C07D307/00; C07D307/02; C07D307/34; C07D307/56; C07D307/60; Y; Y10; Y10S; Y10S436/00; Y10S436/80

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 32 words
A compound of the formula ##STR12## wherein R 2 is phenyl, lower-alkoxyphenyl, di-lower-alkoxyphenyl, R 3 is phenyl, naphthyl or nitrophenyl, and R 4 and R 5 taken independently are each lower alkyl.
Claim 2
Dependent Claim 32 words
A compound of the formula ##STR12## wherein R 2 is phenyl, lower-alkoxyphenyl, di-lower-alkoxyphenyl, R 3 is phenyl, naphthyl or nitrophenyl, and R 4 and R 5 taken independently are each lower alkyl.
Claim 3
Dependent Claim 8 words
The compound of claim 1 which is 1-dimethylamino-2,4-diphenyl-1-buten-3,4-dione.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-08-29 1981-02-28 1981-08-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-08-29 1985-02-28 1985-08-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-08-29 1989-02-28 1989-08-30 $7700.00 Window Closed / Lapsed

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