US4045448A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pyrrolo[2,1-c][1,4]benzoxazepine and benzoxazocine derivatives
Assignee: CNA Holdings LLC
•
Filing: 1976-02-26
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Granted: 1977-08-30
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Expires: 1996-02-26
Abstract
Abstract Novel pyrrolobenzoxazalkanes, physiologically tolerable acid addition salts thereof and a method of preparing same are described. Compounds of the present invention are useful as analgesic, tranquilizing and anticonvulsant agents.
Inventors
- 👤 Richard C. Effland
- 👤 Larry Davis
- 👤 Wolfgang Schaub
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 13:46
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/30; C07D207/32; C07D207/325; A; A61; A61P; A61P25/00; A61P25/04; A61P25/20
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
55 words
A compound of the formula ##STR16## wherein Y is hydrogen, halogen, lower alkoxy, lower alkyl, trifluoromethyl, nitro or amino; R 2 is alkyl, phenylloweralkyl, alkylaminoalkyl, dialkylaminoalkyl or diphenylloweralkyl of the formula ##STR17## and R 3 is hydrogen, alkyl, cycloalkylloweralkyl or phenylloweralkyl; m the integer 1 or 2; or a physiologically tolerable acid addition salt thereof.
Claim 2
Dependent Claim
55 words
A compound of the formula ##STR16## wherein Y is hydrogen, halogen, lower alkoxy, lower alkyl, trifluoromethyl, nitro or amino; R 2 is alkyl, phenylloweralkyl, alkylaminoalkyl, dialkylaminoalkyl or diphenylloweralkyl of the formula ##STR17## and R 3 is hydrogen, alkyl, cycloalkylloweralkyl or phenylloweralkyl; m the integer 1 or 2; or a physiologically tolerable acid addition salt thereof.
Claim 3
Dependent Claim
13 words
A compound as defined in claim 1 wherein m is the integer 1.
Claim 4
Dependent Claim
36 words
A compound as defined in claim 1 wherein Y is hydrogen halogen, nitro or methyl; and R 2 is alkyl, phenylloweralkyl, alkylaminoalkyl, dialkylaminoalkyl, (CH 2 ) n CH--(C 6 H 5 ) 2 or ##STR18## .
Claim 5
Dependent Claim
27 words
A compound as defined in claim 3 wherein Y is hydrogen, R 2 is methyl, phenethyl, N,N-diethylaminoethyl or ##STR19## and R 3 is hydrogen, methyl or cyclopropylmethyl.
Claim 6
Dependent Claim
13 words
A compound as defined in claim 1 wherein m is the integer 2.
Claim 7
Dependent Claim
11 words
The compound defined in claim 1 which is 1-[(N-phenethyl)aminoethyl - 4H,10H-pyrrolo[2,1-c][1,4]benzoxazepine.
Claim 8
Dependent Claim
10 words
The compound defined in claim 1 which is 1-[4,4-bis-(4-fluorophenyl) butylaminomethyl]-4H,10H-pyrrolo[2,1-c][1,4]benzoxazepine.
Claim 9
Dependent Claim
10 words
The compound defined in claim 1 which is 1-methylaminomethyl- 4H,10H-pyrrolo[2,1-c][1,4]benzoxazepine.
Claim 10
Dependent Claim
9 words
The compound defined in claim 1 which is 1-dimethylaminomethyl-4H,10H-pyrrolo[2,1c][1,4]benzoxazepine.
References Cited (Backward Citations)
US3888946A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-29 | 1981-02-28 | 1981-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-29 | 1985-02-28 | 1985-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-29 | 1989-02-28 | 1989-08-30 | $7700.00 | Window Closed / Lapsed |