US4044153A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antiinflammatory 2-aminomethyl-6-trihalomethylphenols
Assignee: Merck and Co Inc
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Filing: 1976-05-07
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Granted: 1977-08-23
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Expires: 1996-05-07
Abstract
Abstract 2-Aminomethylphenol products and their non-toxic, pharmaceutically acceptable salts useful in the treatment of edema and inflammation are disclosed. The products may be prepared by treating an N-(2-hydroxybenzyl)carboxamide with an aqueous solution of an acid or a base.
Inventors
- 👤 Everett M. Schultz
- 👤 Edward J. Cragoe, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 10:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
48 words
A pharamaceutical composition comprising an antiinflammatory effective amount of a compound of the formula: ##STR7## wherein X 1 is C 1-7 lower alkyl, or cycloalkyl containing 5 to 6 carbon atoms; and X 2 is trifluoromethyl; or the non-toxic pharamaceutically acceptable salts thereof in a pharamceutically acceptable carrier.
Claim 2
Dependent Claim
48 words
A pharamaceutical composition comprising an antiinflammatory effective amount of a compound of the formula: ##STR7## wherein X 1 is C 1-7 lower alkyl, or cycloalkyl containing 5 to 6 carbon atoms; and X 2 is trifluoromethyl; or the non-toxic pharamaceutically acceptable salts thereof in a pharamceutically acceptable carrier.
Claim 3
Dependent Claim
10 words
The composition of claim 1 wherein X 1 is tert-butyl.
References Cited (Backward Citations)
US3219701A
Cited
US3399226A
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US3809721A
Cited
US3864401A
Cited
US3794734A
Cited
US3979361A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-22 | 1981-02-21 | 1981-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-22 | 1985-02-21 | 1985-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-22 | 1989-02-21 | 1989-08-23 | $7700.00 | Window Closed / Lapsed |