Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
91 words
A method of treatment of diabetes which comprises administering to a patient an effective amount of a compound of the formula: ##STR6## in which R 1 represents C 1-4 alkyl; aminoethyl; dimethylaminoethyl; 2-ethoxyethyl; allyl; propynyl; benzyl, p-methoxybenzyl; phenoxyethyl; phenacyl or 4-methoxyphenacyl; R 2 represents hydrogen or C 1-4 alkyl; R 3 represents hydrogen; R 4 represents hydrogen; methyl, ethyl; benzyl; or p-methoxyphenyl; R 5 represents C 1-5 alkyl; 2-aminoethyl; 2-hydroxyethyl; 2-ethoxyethyl, 2-methoxyethyl, 3-methoxypropyl, ethoxymethyl; allyl, dimethylallyl; cyclopentyl; benzyl; phenoxyethyl or 3-tetrahydrofuranyl; X represents iodide, bromide, chloride, toluene sulphonate or hydrogen sulphate.
Claim 2
Independent Claim
91 words
A method of treatment of diabetes which comprises administering to a patient an effective amount of a compound of the formula: ##STR6## in which R 1 represents C 1-4 alkyl; aminoethyl; dimethylaminoethyl; 2-ethoxyethyl; allyl; propynyl; benzyl, p-methoxybenzyl; phenoxyethyl; phenacyl or 4-methoxyphenacyl; R 2 represents hydrogen or C 1-4 alkyl; R 3 represents hydrogen; R 4 represents hydrogen; methyl, ethyl; benzyl; or p-methoxyphenyl; R 5 represents C 1-5 alkyl; 2-aminoethyl; 2-hydroxyethyl; 2-ethoxyethyl, 2-methoxyethyl, 3-methoxypropyl, ethoxymethyl; allyl, dimethylallyl; cyclopentyl; benzyl; phenoxyethyl or 3-tetrahydrofuranyl; X represents iodide, bromide, chloride, toluene sulphonate or hydrogen sulphate.
Claim 3
Dependent Claim
24 words
The method of claim 1 wherein R 1 represents methyl, ethyl, isopropyl or butyl; and R 5 represents methyl, ethyl, isopropyl, pentyl or isopentyl.
Claim 4
Dependent Claim
12 words
The method of claim 1 wherein the compound is 6-(2-ethoxyethoxy)-2-methylisoquinolinium bromide monohydrate.
Claim 5
Independent Claim
18 words
A method of treatment of diabetes which comprises administering to a patient an effective amount of 6-ethoxy-2-(2-hydroxyethyl)isoquinolinium bromide.
Claim 6
Independent Claim
18 words
A method of treatment of diabetes which comprises administering to a patient an effective amount of 6-ethoxy-2-(2-hydroxyethyl)isoquinolinium bromide.
Claim 7
Dependent Claim
11 words
The method of claim 1 wherein the compound is administered orally.
Claim 8
Dependent Claim
22 words
The method of claim 5 wherein the effective amount of the compound is in a dosage range of from 5-500 mg daily.
Claim 9
Dependent Claim
11 words
The method of claim 1 wherein the compound is 6-methoxy-2-methylisoquinolinium iodide.
Claim 10
Dependent Claim
11 words
The method of claim 1 wherein the compound is 6-methoxy-2,3-dimethylisoquinolinium iodide.
Claim 11
Dependent Claim
11 words
The method of claim 1 wherein the compound is 6-methoxy-1,2-dimethylisoquinolinium iodide.
Claim 12
Dependent Claim
11 words
The method of claim 1 wherein the compound is 6-ethoxy-2-butylisoquinolinium iodide.
Claim 13
Dependent Claim
13 words
The method of claim 1 wherein the compound is 6-ethoxy-2-ethylisoquinolinium hydrogen sulphate, monohydrate.
Claim 14
Dependent Claim
12 words
The method of claim 1 wherein the compound is 6-ethoxy-2-methylisoquinolinium bromide monohydrate.
Claim 15
Dependent Claim
12 words
The method of claim 1 wherein the compound is 6-ethoxy-2,3-dimethylisoquinolinium bromide monohydrate.