US4041030A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Arylamino pyrimidinic derivatives
Assignee: Synthelabo SA
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Filing: 1976-08-16
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Granted: 1977-08-09
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Expires: 1996-08-16
Abstract
Abstract Compounds of the formula <IMAGE> WHEREIN Ar is phenyl or phenyl substituted by one or more halogens, a trifluoromethyl, a methylenedioxy, one or more methoxy, an alkyl having one to 4 carbon atoms or a dimethylamino, AND R is <IMAGE> wherein R1 and R2 each are hydrogen or alkyl of 1 to 4 carbon atoms, or <IMAGE> PYRROLIDINO, MORPHOLINO, PIPERIDINO OR PIPERAZINO N'-substituted by alkyl of 1 to 4 carbon atoms, or phenyl, or R is para-2-morpholino ethylamino carbonyl, and R3 is hydrogen or methyl.
Inventors
- 👤 Claude P. Fauran
- 👤 Guy R. Bourgery
- 👤 Guy M. Raynaud
- 👤 Claude J. Gouret
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:58
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/12; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/32; C07D239/42
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
58 words
A compound having the formula ##STR33## in which a. Ar is p-chlorophenyl and R is morpholino or piperidino, or b. Ar is o-chlorophenyl and R is morpholino, or c. Ar is m-fluorophenyl and R is piperidino, or d. Ar is 3,4-methylenedioxyphenyl and R is morpholino or amino, or e. Ar is 3,4,5-trimethoxyphenyl and R is morpholino or amino.
Claim 2
Dependent Claim
58 words
A compound having the formula ##STR33## in which a. Ar is p-chlorophenyl and R is morpholino or piperidino, or b. Ar is o-chlorophenyl and R is morpholino, or c. Ar is m-fluorophenyl and R is piperidino, or d. Ar is 3,4-methylenedioxyphenyl and R is morpholino or amino, or e. Ar is 3,4,5-trimethoxyphenyl and R is morpholino or amino.
Claim 3
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is p-chlorophenyl, R is morpholino and ##STR34## is a para position.
Claim 4
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is p-chlorophenyl, R is morpholino and ##STR35## is in meta position.
Claim 5
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is p-chlorophenyl, R is morpholino and ##STR36## is in ortho position.
Claim 6
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is p-chlorophenyl, R is piperidino and ##STR37## is in para position.
Claim 7
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is m-fluorophenyl, R is piperidino and ##STR38## is in para position.
Claim 8
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is 3,4-methylenedioxyphenyl, R is morpholino and ##STR39## is in para position.
Claim 9
Dependent Claim
22 words
A compound as claimed in claim 1 in which Ar is 3,4-methylenedioxyphenyl, R is --NH 2 and ##STR40## is in ortho position.
Claim 10
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is 3,4,5-trimethoxyphenyl, R is morpholino and ##STR41## is in para position.
Claim 11
Dependent Claim
22 words
A compound as claimed in claim 1 in which Ar is 3,4,5-trimethoxyphenyl, R is --NH 2 and ##STR42## is in para position.
Claim 12
Dependent Claim
21 words
A compound as claimed in claim 1 in which Ar is o-chlorophenyl, R is morpholino and ##STR43## is in para position.
Claim 13
Dependent Claim
27 words
A compound having the formula ##STR44## in which Ar is phenyl or phenyl substituted by a halogen, R is ##STR45## and R 3 is hydrogen or methyl.
Claim 14
Dependent Claim
27 words
A compound having the formula ##STR44## in which Ar is phenyl or phenyl substituted by a halogen, R is ##STR45## and R 3 is hydrogen or methyl.
Claim 15
Dependent Claim
23 words
A compound as claimed in claim 12 in which Ar is phenyl, R is ##STR46## in para position and R 3 is methyl.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-08 | 1981-02-07 | 1981-08-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-08 | 1985-02-07 | 1985-08-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-08 | 1989-02-07 | 1989-08-09 | $7700.00 | Window Closed / Lapsed |