US4040785A
Expired / Lapsed
US
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Lysable blood preservative composition
Assignee: Bayer Corp
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Filing: 1976-10-18
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Granted: 1977-08-09
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Expires: 1996-10-18
Abstract
Abstract Blood is preserved by combining samples with a preservative reagent consisting of an aqueous mixture of a mono-, di- or trisaccharide component and formaldehyde.
Inventors
- 👤 Young Ran Kim
- 👤 Leonard Ornstein
- 👤 Henry Cook Waters, III
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 16:26
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/12; A61K35/14; A01; A01N; A01N1/00; A01N1/10; A01N1/12; A01N1/122; A01N1/124; A01N1/126; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/105831; Y10T436/107497; Y10T436/108331; Y10T436/25; Y10T436/2525
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
63 words
A preserved lysable anticoagulated blood composition comprising a mixture of blood sample and preservative reagent wherein said preservative reagent comprises an aqueous mixture of a mono-, di- or trisaccharide component and formaldehyde, the resulting preserved blood composition containing said saccharide in the range of from 0.05% to 1.0% by weight and said formaldehyde in the range of from 0.1% to 0.8% by weight.
Claim 2
Dependent Claim
63 words
A preserved lysable anticoagulated blood composition comprising a mixture of blood sample and preservative reagent wherein said preservative reagent comprises an aqueous mixture of a mono-, di- or trisaccharide component and formaldehyde, the resulting preserved blood composition containing said saccharide in the range of from 0.05% to 1.0% by weight and said formaldehyde in the range of from 0.1% to 0.8% by weight.
Claim 3
Dependent Claim
13 words
The blood composition of claim 1 wherein said saccharide component is a monosaccharide.
Claim 4
Dependent Claim
32 words
The blood composition of claim 2 wherein said monosaccharide is dextrose and the resulting preserved blood composition contains dextrose and formaldehyde in amounts of 1% by weight and 0.2% by weight respectively.
Claim 5
Dependent Claim
32 words
The blood composition of claim 2 wherein said monosaccharide is dextrose and the resulting preserved blood composition contains dextrose and formaldehyde in amounts of 0.66% by weight and 0.13% by weight respectively.
Claim 6
Dependent Claim
91 words
In a method for enhancing the preservative characteristics of whole blood samples comprising a mixture of whole blood sample and preservative reagent, the improvement which comprises adding a filtered aqueous mixture of a mono-, di- or trisaccharide component and formaldehyde to a fresh whole blood sample, the resulting preserved anticoagulated blood composition containing said saccharide in the range of from 0.05% to 1.0% by weight and said formaldehyde in the range of from 0.1% to 0.8% by weight, mixing the resulting preserved blood composition and storing same until ready for testing.
Claim 7
Dependent Claim
91 words
In a method for enhancing the preservative characteristics of whole blood samples comprising a mixture of whole blood sample and preservative reagent, the improvement which comprises adding a filtered aqueous mixture of a mono-, di- or trisaccharide component and formaldehyde to a fresh whole blood sample, the resulting preserved anticoagulated blood composition containing said saccharide in the range of from 0.05% to 1.0% by weight and said formaldehyde in the range of from 0.1% to 0.8% by weight, mixing the resulting preserved blood composition and storing same until ready for testing.
Claim 8
Dependent Claim
13 words
The method of claim 5 wherein anticoagulent is contained in the preservative reagent.
Claim 9
Dependent Claim
13 words
The method of claim 5 wherein anticoagulent is contained in the blood sample.
Claim 10
Dependent Claim
12 words
The method of claim 5 wherein said saccharide component is a monosaccharide.
Claim 11
Dependent Claim
37 words
The method of claim 8 wherein said monosaccharide is dextrose and the resulting preserved blood composition contains dextrose and formaldehyde in amounts of 1% by weight and 0.2% by weight respectively and is stored at 4° C.
Claim 12
Dependent Claim
37 words
The method of claim 8 wherein said monosaccharide is dextrose and the resulting preserved blood composition contains dextrose and formaldehyde in amounts of 0.66% by weight and 0.13% by weight respectively and is stored at 25° C.
Claim 13
Dependent Claim
16 words
The method of claim 5 wherein said aqueous mixture is filtered through an 0.8 μ filter.
Claim 14
Dependent Claim
25 words
The method of claim 5 wherein said resulting preserved blood composition is stored at a temperature in the range from 1° C. to 25° C.
Claim 15
Dependent Claim
13 words
The method of claim 5 wherein said mixing step is accomplished by inversion.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-08 | 1981-02-07 | 1981-08-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-08 | 1985-02-07 | 1985-08-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-08 | 1989-02-07 | 1989-08-09 | $7700.00 | Window Closed / Lapsed |