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US4039835A Expired / Lapsed US ⏱️ 0.0 years remaining

Reloadable radioactive generator system

Assignee: Individual
•
Filing: 1976-03-12
•
Granted: 1977-08-02
•
Expires: 1996-03-12
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Abstract

Abstract A generator system that can be reloaded with an elutable radioactive material, such as 99 molybdenum, a multiple number of times is described. The system basically comprises a column filled with alumina, a loading vial containing a predetermined amount of the elutable radioactive material, and a rinsing vial containing a sterile solution. The two vials are connected by a conduit so that when communication is achieved between the column and loading vial and an evacuated vial is placed in communication with the bottom of the column, the predetermined amount of the radioactive material in the loading vial will be transferred to the column. The procedure can be repeated as the elutable material in the column is dissipated.

Inventors

  • 👤 Lelio G. Colombetti

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 22:24
CPC Classifications
G; G21; G21G; G21G1/00; G21G1/04; G21G1/0005

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 146 words
A generator system that can be reloaded with an elutable radioactive material which can be used for nuclear medicine and which comprises: an elongated column having a chromatographic bed of alumina therein and sealed at the top and bottom thereof; transfer means arranged at the top and bottom of the column for communication with separate containers; a first container having a predetermined amount of elutable radioactive material therein and adapted for attachment to the transfer means arranged at the top of the column; a second container having a rinsing solution therein; and conduit means connecting the first and second containers whereby the elutable radioactive material and rinsing solution will be transferred to the column when the first container is attached to the transfer means at the top of the column and an evacuated container is attached to the transfer means at the bottom of the column.
Claim 2
Dependent Claim 146 words
A generator system that can be reloaded with an elutable radioactive material which can be used for nuclear medicine and which comprises: an elongated column having a chromatographic bed of alumina therein and sealed at the top and bottom thereof; transfer means arranged at the top and bottom of the column for communication with separate containers; a first container having a predetermined amount of elutable radioactive material therein and adapted for attachment to the transfer means arranged at the top of the column; a second container having a rinsing solution therein; and conduit means connecting the first and second containers whereby the elutable radioactive material and rinsing solution will be transferred to the column when the first container is attached to the transfer means at the top of the column and an evacuated container is attached to the transfer means at the bottom of the column.
Claim 3
Dependent Claim 31 words
The generator system of claim 1 wherein the transfer means arranged at the top of the column comprises a needle projecting outwardly through the seal thereof and communicating with the column.
Claim 4
Dependent Claim 26 words
The generator system of claim 2 wherein the transfer means arranged at the bottom of the column comprises a needle arranged for communication with the column.
Claim 5
Dependent Claim 14 words
The generator system of claim 3 wherein the elutable radioactive material contains molybdenum 99.
Claim 6
Dependent Claim 13 words
The generator system of claim 3 wherein the second container includes venting means.
Claim 7
Dependent Claim 24 words
The generator system of claim 5 wherein the chromatographic bed of alumina is retained between two spaced apart porous disks fitted within the column.
Claim 8
Dependent Claim 20 words
The generator system of claim 6 wherein a filter is interposed between the bottom of the column and the needle.
Claim 9
Independent Claim 139 words
A method of reloading a generator system comprising an elongated column containing a chromatographic bed of alumina therein and including transfer means at the top and bottom of the column for communication with separate containers, said method comprising the steps of: providing a first container having a predetermined amount of elutable radioactive material therein and adapted for attachment to the transfer means arranged at the top of the column; providing a second container having a rinsing solution and conduit means connecting the first and second containers; attaching the first container to the transfer means arranged to the top of the column to provide communication between the column and the first container; and attaching an evacuated container to the transfer means at the bottom of the container, whereby the elutable radioactive material and rinsing solution are transferred into the column.
Claim 10
Independent Claim 139 words
A method of reloading a generator system comprising an elongated column containing a chromatographic bed of alumina therein and including transfer means at the top and bottom of the column for communication with separate containers, said method comprising the steps of: providing a first container having a predetermined amount of elutable radioactive material therein and adapted for attachment to the transfer means arranged at the top of the column; providing a second container having a rinsing solution and conduit means connecting the first and second containers; attaching the first container to the transfer means arranged to the top of the column to provide communication between the column and the first container; and attaching an evacuated container to the transfer means at the bottom of the container, whereby the elutable radioactive material and rinsing solution are transferred into the column.
Claim 11
Dependent Claim 13 words
The method of claim 8 wherein the elutable radioactive material contains molybdenum 99.
Claim 12
Dependent Claim 12 words
The method of claim 9 wherein the rinsing solution comprises saline solution.

References Cited (Backward Citations)

US3576998A Cited
US3774035A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-08-01 1981-01-31 1981-08-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-08-01 1985-01-31 1985-08-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-08-01 1989-01-31 1989-08-02 $7700.00 Window Closed / Lapsed

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