US4038402A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of effecting antihistaminic, antiserotonin and antiallergic actions
Assignee: Individual
•
Filing: 1976-07-15
•
Granted: 1977-07-26
•
Expires: 1996-07-15
Abstract
Abstract Antihistaminic, antiserotonin and antiallergic effects are achieved by administering to a subject requiring the same a (quinuclidyl-3)-diaryl (heteryl)carbinol of the formula: ##STR1## wherein n is 0 or 1, wherein R and R' are the same or different substituted, unsubstituted or hydrated phenyl or heteroaryl and wherein A is either absent or is a physiologically compatible acid such as hydrogen chloride, hydrogen bromide, phosphoric acid, sulphuric acid, maleic acid, adipic acid, citric acid, tartaric acid, benzoic acid, or fumaric acid.
Inventors
- 👤 Mikhail Emmanuilovich Kaminka
- 👤 Eva Evseevna Mikhlina
- 👤 Valentina Yakovlevna Vorobieva
- 👤 Anna Dmitrievna Yanina
- 👤 Nadezhda Andreevna Komarova
- 👤 Mikhail Davidovich Mashkovsky
- 👤 Leonid Nikolaevich Yakhontov
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 21:52
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; C; C07; C07D; C07D453/00; C07D453/02
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
87 words
Method of effecting at least one of the actions of antihistaminic, antiserotonin and antiallergic action, which comprises administering to a subject requiring such action a corresponding effective dose of a compound of the formula: ##STR3## where n is selected from the group consisting of 0 and 1, wherein R and R 1 are each selected from the group consisting of phenyl loweralkoxy phenyl, loweralkyl phenyl, lower dialkyl phenyl, thienyl, chlorophenyl, benzoyl, cyclohexyl, phenylketone and clorophenyl ketone, and wherein A is absent or is a physiologically compatible acid.
Claim 2
Dependent Claim
87 words
Method of effecting at least one of the actions of antihistaminic, antiserotonin and antiallergic action, which comprises administering to a subject requiring such action a corresponding effective dose of a compound of the formula: ##STR3## where n is selected from the group consisting of 0 and 1, wherein R and R 1 are each selected from the group consisting of phenyl loweralkoxy phenyl, loweralkyl phenyl, lower dialkyl phenyl, thienyl, chlorophenyl, benzoyl, cyclohexyl, phenylketone and clorophenyl ketone, and wherein A is absent or is a physiologically compatible acid.
Claim 3
Dependent Claim
41 words
Method according to claim 1 wherein A is present and is a physiologically acid selected from the group consisting of hydrogen chloride, hydrogen bromide, phosphoric acid, sulphuric acid, maleic acid, adipic acid, citric acid, tartaric acid, benzoic acid and fumaric acid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-07-25 | 1981-01-24 | 1981-07-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-07-25 | 1985-01-24 | 1985-07-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-07-25 | 1989-01-24 | 1989-07-26 | $7700.00 | Window Closed / Lapsed |