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US4035498A Expired / Lapsed US ⏱️ 0.0 years remaining

Pharmaceutically active compounds and the preparation thereof

Assignee: Centre Europeen de Recherches Mauvernay CERM
•
Filing: 1975-09-29
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Granted: 1977-07-12
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Expires: 1995-09-29
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Abstract

Abstract Compounds of the formula: <IMAGE> wherein R is a lower alkyl group, X is oxygen or the group -(CH2)n- where n is 0 or 1, having bronchospasmolytic activity, are described.

Inventors

  • 👤 Roland Yves Mauvernay
  • 👤 Norbert Busch
  • 👤 Jacques Moleyre
  • 👤 Jacques Simond
  • 👤 Andre Monteil

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 19:12
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/08; C07D295/084; C07D295/092; A; A61; A61P; A61P11/00; A61P11/08; A61P11/14; C07D311/00; C07D311/02; C07D311/04; C07D311/22

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 50 words
A compound selected from the group consisting of those of the formula: ##STR11## and pharmaceutically acceptable acid addition salts thereof, in which R represents a methyl or ethyl group and X represents an oxygen atom or a group --(CH 2 ) n -- in which n is 0 or 1.
Claim 2
Dependent Claim 50 words
A compound selected from the group consisting of those of the formula: ##STR11## and pharmaceutically acceptable acid addition salts thereof, in which R represents a methyl or ethyl group and X represents an oxygen atom or a group --(CH 2 ) n -- in which n is 0 or 1.
Claim 3
Dependent Claim 3 words
3[4-(2-Methoxy-2-phenyl)-ethyl piperazinyl] -methyl-4-hydroxy-chromane.
Claim 4
Dependent Claim 3 words
3[4-(2-Methoxy-2-phenyl)-ethyl piperazinyl] -methyl-4-hydroxy-chromane.
Claim 5
Dependent Claim 3 words
2-[4-(2-Ethoxy 2-phenyl)-ethyl-piperazinyl] -methyl-tetralol.
Claim 6
Dependent Claim 3 words
2-[4-(2-Ethoxy 2-phenyl)-ethyl-piperazinyl] -methyl-tetralol.
Claim 7
Dependent Claim 5 words
2-[4-(2-Methoxy 2-phenyl)ethyl piperazinyl] -methyl tetralol.
Claim 8
Dependent Claim 5 words
2-[4-(2-Methoxy 2-phenyl)ethyl piperazinyl] -methyl tetralol.
Claim 9
Dependent Claim 4 words
1-Hydroxy-2-[4-(2-methoxy 2-phenyl)ethyl-piperazinyl] methyl indane.
Claim 10
Dependent Claim 4 words
1-Hydroxy-2-[4-(2-methoxy 2-phenyl)ethyl-piperazinyl] methyl indane.
Claim 11
Dependent Claim 21 words
A pharmaceutical composition consisting essentially of a compound as claimed in claim 1 in association with a pharmaceutical carrier or diluent.
Claim 12
Dependent Claim 32 words
The application of a compound as claimed in claim 1 in the treatment of bronchopulmonary conditions in the form of orally administrable compositions at daily dosages of from 10 to 500 mg.

References Cited (Backward Citations)

US3753985A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-07-11 1981-01-10 1981-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-07-11 1985-01-10 1985-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-07-11 1989-01-10 1989-07-12 $7700.00 Window Closed / Lapsed

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