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US4035492A Expired / Lapsed US ⏱️ 0.0 years remaining

Oral treatment of seborrhea with cysteamine derivatives

Assignee: L'Oréal SA
•
Filing: 1976-01-29
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Granted: 1977-07-12
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Expires: 1996-01-29
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Abstract

Abstract A method for treating a scalp characterized by an excessive secretion of sebum, to improve the condition thereof by reducing said excessive secretion comprising orally administering to a human being having a scalp so characterized a therapeutic composition comprising an ingestible carrier admixed with, as a non-toxic active compound, cysteine or cysteamine derivatives, the active compound is present in amounts of about 0.75-3 weight percent of the composition which is administered at a rate of about 1-5 mg/kg/day based on the weight of the human being during a period of about 15 days.

Inventors

  • 👤 Gregoire Kalopissis
  • 👤 Georges Mandussos

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 20:34
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61K8/447; A61K8/46; A61Q; A61Q5/00; A61Q5/008; A61K2800/00; A61K2800/80; A61K2800/92; Y; Y10; Y10S; Y10S424/00; Y10S424/04

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 192 words
A method for treating a scalp, characterized by an excessive secretion of sebum, to improve the condition thereof by reducing said excessive secretion of sebum comprising orally administering to a human being having a scalp so characterized a therapeutic composition comprising an ingestible carrier admixed with a non-toxic active compound selected from the group consisting of: 2-phenylthio ethylamine dihydrogen phosphate, 2-p-t-butylphenylthio ethylamine trichloracetate, 2-p-methoxyphenylthio ethylamine ditartrate, 2-tolylthio ethylamine hydrobromide, 2-(1-biphenyl thio) ethylamine hydrochloride, 2-benzylthio 2-methyl propylamine hydrochloride, 2-benzylthio propylamine lactate, 2-o-aminophenylthio ethylamine succinate, 2-(2-naphthyl methylthio) ethylamine hydrochloride, 2-(2-naphthyl methylthio) ethylamine disuccinate, 2-o-chlorobenzylthio ethylamine hydrochloride, 2-p-chlorobenzylthio ethylamine glycolate, 2-o-fluorobenzylthio ethylamine hydrochloride, 2-β-phenylethylthio ethylamine glutamate, 2-diphenylmethylthio ethylamine hydrochloride, 2,4-dichloro 2-benzylthio ethylamine aspartate, 2-o-methoxy benzylthio ethylamine hydrochloride, 2-p-ethoxybenzylthio ethylamine hydrochloride, 2-p-bromobenzylthio ethylamine succinate, 2-(3,4-dimethoxy benzylthio) ethylamine malate, 2-(3,4,5-trimethoxy benzylthio) ethylamine hydrocinnamate, 2-p-methoxy benzylthio ethylamine salicylate, 2-o-methylbenzylthio ethylamine phenylacetate, 2-p-phenoxybenzylthio ethylamine hydrochloride, 2-benzylthio ethylamine panthothenate, 2-p-nitrobenzylthio ethylamine crotonate, 2-(1-naphthyl thio) ethylamine hydrochloride, 2-benzylthio propylamine and 2-benzylthio 2-methyl propylamine, said active compound being present in an amount ranging from 0.75 to 3 percent by weight of said composition and said composition being administered at a rate of 1.5-5 mg/kg/day based on the weight of the human being.
Claim 2
Independent Claim 192 words
A method for treating a scalp, characterized by an excessive secretion of sebum, to improve the condition thereof by reducing said excessive secretion of sebum comprising orally administering to a human being having a scalp so characterized a therapeutic composition comprising an ingestible carrier admixed with a non-toxic active compound selected from the group consisting of: 2-phenylthio ethylamine dihydrogen phosphate, 2-p-t-butylphenylthio ethylamine trichloracetate, 2-p-methoxyphenylthio ethylamine ditartrate, 2-tolylthio ethylamine hydrobromide, 2-(1-biphenyl thio) ethylamine hydrochloride, 2-benzylthio 2-methyl propylamine hydrochloride, 2-benzylthio propylamine lactate, 2-o-aminophenylthio ethylamine succinate, 2-(2-naphthyl methylthio) ethylamine hydrochloride, 2-(2-naphthyl methylthio) ethylamine disuccinate, 2-o-chlorobenzylthio ethylamine hydrochloride, 2-p-chlorobenzylthio ethylamine glycolate, 2-o-fluorobenzylthio ethylamine hydrochloride, 2-β-phenylethylthio ethylamine glutamate, 2-diphenylmethylthio ethylamine hydrochloride, 2,4-dichloro 2-benzylthio ethylamine aspartate, 2-o-methoxy benzylthio ethylamine hydrochloride, 2-p-ethoxybenzylthio ethylamine hydrochloride, 2-p-bromobenzylthio ethylamine succinate, 2-(3,4-dimethoxy benzylthio) ethylamine malate, 2-(3,4,5-trimethoxy benzylthio) ethylamine hydrocinnamate, 2-p-methoxy benzylthio ethylamine salicylate, 2-o-methylbenzylthio ethylamine phenylacetate, 2-p-phenoxybenzylthio ethylamine hydrochloride, 2-benzylthio ethylamine panthothenate, 2-p-nitrobenzylthio ethylamine crotonate, 2-(1-naphthyl thio) ethylamine hydrochloride, 2-benzylthio propylamine and 2-benzylthio 2-methyl propylamine, said active compound being present in an amount ranging from 0.75 to 3 percent by weight of said composition and said composition being administered at a rate of 1.5-5 mg/kg/day based on the weight of the human being.

References Cited (Backward Citations)

US2769839A Cited
US2835704A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-07-11 1981-01-10 1981-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-07-11 1985-01-10 1985-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-07-11 1989-01-10 1989-07-12 $7700.00 Window Closed / Lapsed

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