← Back to Patent Explorer
US4035087A Expired / Lapsed US ⏱️ 0.0 years remaining

Chemical reaction velocity measuring apparatus

Assignee: Nikon Corp
•
Filing: 1975-12-16
•
Granted: 1977-07-12
•
Expires: 1995-12-16
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract An apparatus for measuring a chemical reaction velocity of a sample whose light absorbance changes in proportion to time, comprises a differential circuit for converting the absorbance signals at two different times into respective first-order differential signals, or an integrating circuit for integrating the variation of absorbance signal at two times into two integrated signals. A subtractor is provided to obtain the difference of the two differential signals or two integrated signals. The output of the subtractor is compared with a standard level by a comparing means so that abnormality signal is indicated when said difference does not fall into the standard level.

Inventors

  • 👤 Hidetoshi Mori
  • 👤 Teruo Shimamura
  • 👤 Yoshio Fukami

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 21:06
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/17; G01N21/25; G01N21/27; G01N21/272

Claims Analysis

Total Claims: 24
Claim 1
Independent Claim 96 words
An apparatus for measuring reaction velocity of a sample from the difference of light absorbance measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, comprising a differentiating circuit for converting the absorbance signals at said two times into respective first-order differential signals, a subtractor for obtaining the difference of said two differential signals, and a comparing means for comparing the output of said subtractor with a standard level, an abnormality signal being indicated when said difference of first-order differential signals does not fall into said standard level.
Claim 2
Independent Claim 96 words
An apparatus for measuring reaction velocity of a sample from the difference of light absorbance measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, comprising a differentiating circuit for converting the absorbance signals at said two times into respective first-order differential signals, a subtractor for obtaining the difference of said two differential signals, and a comparing means for comparing the output of said subtractor with a standard level, an abnormality signal being indicated when said difference of first-order differential signals does not fall into said standard level.
Claim 3
Independent Claim 93 words
An apparatus for measuring reaction velocity of a sample from the difference of light absorbance of measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, comprising an integrating circuit for integrating the variation of absorbance signal at said two times, a subtractor for obtaining the difference of said two integrated signals, and a comparing means for comparing the output of said subtractor with a standard level, an abnormality signal being indicated when said difference of integrated signals does not fall into said standard level.
Claim 4
Independent Claim 93 words
An apparatus for measuring reaction velocity of a sample from the difference of light absorbance of measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, comprising an integrating circuit for integrating the variation of absorbance signal at said two times, a subtractor for obtaining the difference of said two integrated signals, and a comparing means for comparing the output of said subtractor with a standard level, an abnormality signal being indicated when said difference of integrated signals does not fall into said standard level.
Claim 5
Dependent Claim 115 words
In combination with apparatus for measuring the reaction velocity of a sample from the difference of light absorbance measurements taken at two different times, means operative to identify a non-linear condition of said reaction velocity at said times, said means comprising: a circuit operative in response to said light absorbance measurements taken at said two times to produce control signals corresponding to the rates of change of light absorbance of said reaction velocity at each of said two different times, a subtractor for obtaining the difference of said two control signals, and means operative to produce an abnormality signal in response to the output of said subtractor when such output exceeds a predetermined standard level.
Claim 6
Dependent Claim 115 words
In combination with apparatus for measuring the reaction velocity of a sample from the difference of light absorbance measurements taken at two different times, means operative to identify a non-linear condition of said reaction velocity at said times, said means comprising: a circuit operative in response to said light absorbance measurements taken at said two times to produce control signals corresponding to the rates of change of light absorbance of said reaction velocity at each of said two different times, a subtractor for obtaining the difference of said two control signals, and means operative to produce an abnormality signal in response to the output of said subtractor when such output exceeds a predetermined standard level.
Claim 7
Dependent Claim 17 words
The combination according to claim 3, wherein said circuit to produce control signals is a differentiating circuit.
Claim 8
Dependent Claim 17 words
The combination according to claim 3, wherein said circuit to produce control signals is an integrating circuit.
Claim 9
Dependent Claim 98 words
In apparatus for measuring reaction velocity of measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, including: means for measuring the rate of light absorbance of the sample at two different times and indicating a value based upon the difference between said absorbance rates, the combination of a differentiating circuit for converting the absorbance signals at said two different times into respective first-order differential signals, a subtractor for obtaining the difference between said two differential signals, and means for comparing the output of said subtractor with a standard level.
Claim 10
Dependent Claim 98 words
In apparatus for measuring reaction velocity of measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, including: means for measuring the rate of light absorbance of the sample at two different times and indicating a value based upon the difference between said absorbance rates, the combination of a differentiating circuit for converting the absorbance signals at said two different times into respective first-order differential signals, a subtractor for obtaining the difference between said two differential signals, and means for comparing the output of said subtractor with a standard level.
Claim 11
Dependent Claim 38 words
The combination according to claim 6, including display means for indicating the value based upon the difference between said absorbance rates, and means for indicating the relationship of the difference between said differential signals and said standard level.
Claim 12
Dependent Claim 44 words
The combination according to claim 6, wherein said first mentioned means include means for directing light signals of a selected wavelength to a sample, means converting light transmitted from the sample to absorbance signals, and converter means converting said signal into a digital indication.
Claim 13
Dependent Claim 19 words
The combination according to claim 6, including timing means for actuating said differential circuit at said two different times.
Claim 14
Dependent Claim 13 words
The combination according to claim 7, wherein said display means is a printer.
Claim 15
Dependent Claim 30 words
The combination according to claim 8, wherein said first mentioned means include a logarithmic converter and means feeding the signals from same to said converter means and said differential circuit.
Claim 16
Dependent Claim 102 words
In apparatus for measuring reaction velocity of a sample from the difference of light absorbance measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, including: means for measuring the rate of light absorbance of the sample at two different times and indicating a value based upon the difference between said absorbance rates, the combination of an integrating circuit for integrating the variation of absorbance signals at said two times, a subtractor for obtaining the difference between said two integrated signals, and means for comparing the output of said subtractor with a standard level.
Claim 17
Dependent Claim 102 words
In apparatus for measuring reaction velocity of a sample from the difference of light absorbance measurements at two different times effected during a period wherein said absorbance is proportional to the reaction time, including: means for measuring the rate of light absorbance of the sample at two different times and indicating a value based upon the difference between said absorbance rates, the combination of an integrating circuit for integrating the variation of absorbance signals at said two times, a subtractor for obtaining the difference between said two integrated signals, and means for comparing the output of said subtractor with a standard level.
Claim 18
Dependent Claim 37 words
The combination according to claim 12, including display means for indicating the value based upon the difference between said absorbance rates, and means indicating the relationship of the difference between said integrated signals and said standard level.
Claim 19
Dependent Claim 44 words
The combination according to claim 12, wherein said first mentioned means include means for directing light signals of a selected wavelength to a sample, means converting light transmitted from the sample to absorbance signals, and converter means converting said signal into a digital indication.
Claim 20
Dependent Claim 19 words
The combination according to claim 12, including timing means for actuating said integrating circuit at said two different times.
Claim 21
Dependent Claim 13 words
The combination according to claim 13, wherein said display means is a printer.
Claim 22
Dependent Claim 30 words
The combination according to claim 14, wherein said first mentioned means include a logarithmic converter and means feeding the signals from same to said converter means and said integrating circuit.
Claim 23
Independent Claim 87 words
A method for measuring the reaction velocity of a sample from the difference of light absorbance measurements taken at two different times, and identifying a non-linear condition of the reaction velocity at said times, comprising: producing control signals corresponding to the rates of change of light absorbance of the reaction velocity of said sample at each of said two different times, obtaining the difference of said two control signals, and producing an abnormality signal in response to said difference when such output exceeds a predetermined standard level.
Claim 24
Independent Claim 87 words
A method for measuring the reaction velocity of a sample from the difference of light absorbance measurements taken at two different times, and identifying a non-linear condition of the reaction velocity at said times, comprising: producing control signals corresponding to the rates of change of light absorbance of the reaction velocity of said sample at each of said two different times, obtaining the difference of said two control signals, and producing an abnormality signal in response to said difference when such output exceeds a predetermined standard level.

References Cited (Backward Citations)

US3790279A Cited
US3901600A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-07-11 1981-01-10 1981-07-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-07-11 1985-01-10 1985-07-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-07-11 1989-01-10 1989-07-12 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag