US4032633A
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Polypeptides
Assignee: Imperial Chemical Industries Ltd
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Filing: 1975-08-18
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Granted: 1977-06-28
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Expires: 1995-08-18
Abstract
Abstract A polypeptide having 47 amino-acid residues which is obtained by enzymic degradation of urogastrone. The polypeptide obtained is a potent inhibitor of the secretion of acidic gastric juice and is of value in the treatment of duodenal ulcers.
Inventors
- 👤 Harold Gregory
- 👤 Beryl Margaret Preston
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:08
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/475; C07K14/485; A; A61; A61P; A61P1/00; A61K; A61K38/00; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/12
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
17 words
The polypeptide of the formula: or its reduction product in which the cystine residues are reduced to
Claim 2
Dependent Claim
17 words
The polypeptide of the formula: or its reduction product in which the cystine residues are reduced to
Claim 3
Dependent Claim
19 words
A pharmaceutical composition for parenteral administration comprising a polypeptide or reduction product as defined in claim 1 and a
Claim 4
Dependent Claim
22 words
A composition as claimed in claim 2 which is a sterile, injectable solution or suspension containing from 0.5 to 500 μg./ml. of
Claim 5
Dependent Claim
24 words
A pharmaceutical composition comprising from 10 to 200 μg. of sterile polypeptide or reduction product as defined in claim 1 enclosed in a vial
Claim 6
Dependent Claim
34 words
A method of inhibiting the secretion of acidic gastric juice in warm blooded animals which comprises administering to said animal an effective amount of a polypeptide or reduction product as defined in claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-06-27 | 1980-12-27 | 1981-06-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-06-27 | 1984-12-27 | 1985-06-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-06-27 | 1988-12-27 | 1989-06-28 | $7700.00 | Window Closed / Lapsed |