US4029548A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for producing antibiotics U-50,147 and U-51,738
Assignee: Pharmacia and Upjohn Co
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Filing: 1976-05-07
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Granted: 1977-06-14
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Expires: 1996-05-07
Abstract
Abstract Microbiological process for preparing the known antibiotics, antibiotic A-396-1 also known as U-50,147 and L-dihydrophenylalanine also known as U-51,748, by use of the new microorganism Streptomyces lemensis, NRRL 8170 using controlled fermentation conditions. These antibiotics are active against Gram-positive and Gram-negative bacteria. Accordingly, they can be used in various environments to eradicate or control such bacteria.
Inventors
- 👤 Alexander D. Argoudelis
- 👤 LeRoy E. Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 21:05
CPC Classifications
C; C07; C07G; C07G11/00; Y; Y10; Y10S; Y10S435/00; Y10S435/803; Y10S435/8215; Y10S435/822; Y10S435/886
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
35 words
A process for preparing antibiotic U-50,147 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 2
Dependent Claim
35 words
A process for preparing antibiotic U-50,147 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 3
Dependent Claim
20 words
A process, according to claim 1, wherein said aqueous nutrient medium contains a source of assimilable carbohydrate and assimilable nitrogen.
Claim 4
Dependent Claim
35 words
A process for preparing antibiotic U-51,738 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 5
Dependent Claim
35 words
A process for preparing antibiotic U-51,738 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 6
Dependent Claim
20 words
A process, according to claim 3, wherein said aqueous nutrient medium contains a source of assimilable carbohydrate and assimilable nitrogen.
Claim 7
Dependent Claim
40 words
A process for preparing a mixture of antibiotics U-50,174 and U-51,738 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 8
Dependent Claim
40 words
A process for preparing a mixture of antibiotics U-50,174 and U-51,738 which comprises cultivating Streptomyces lemensis, having the identifying characteristics of NRRL 8170 in an aqueous nutrient medium under aerobic conditions until substantial antibiotic activity is imparted to said medium.
Claim 9
Dependent Claim
20 words
A process, according to claim 5, wherein said aqueous nutrient medium contains a source of assimilable carbohydrate and assimilable nitrogen.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-06-13 | 1980-12-13 | 1981-06-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-06-13 | 1984-12-13 | 1985-06-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-06-13 | 1988-12-13 | 1989-06-14 | $7700.00 | Window Closed / Lapsed |