US4028352A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Benzamidopiperidine derivatives
Assignee: John Wyeth and Brother Ltd
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Filing: 1976-04-20
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Granted: 1977-06-07
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Expires: 1996-04-20
Abstract
Abstract A group of heterocyclic compounds useful in the treatment of disorders and diseases of the cardiovascular system is described. These compounds are piperidine compounds linked by the nitrogen atom to a halogen-substituted or unsubstituted phenyl radical through the intermediary of a ##STR1## GROUP WHEREIN N IS AN INTEGER FROM 1 TO 4, AND Ar represents phenyl or halophenyl. The piperidine rings are further substituted by a benzamido residue.
Inventors
- 👤 John Frederick Cavalla
- 👤 John Leheup Archibald
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 03:27
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/72; C07D213/75; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/56; C07D211/58; C07D211/68; C07D211/72; C07D333/00; C07D333/02; C07D333/04; C07D333/06; C07D333/14; C07D333/16; C07D333/50; C07D333/52; C07D333/54; C07D333/56
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
45 words
A compound selected from the group consisting of (A) heterocyclic compounds of formula Ia ##STR18## where n denotes an integer from 1 to 4, Ar represents phenyl or monohalophenyl and R represents phenyl and (B) the pharmaceutically acceptable acid addition and quaternary ammonium salts thereof.
Claim 2
Dependent Claim
45 words
A compound selected from the group consisting of (A) heterocyclic compounds of formula Ia ##STR18## where n denotes an integer from 1 to 4, Ar represents phenyl or monohalophenyl and R represents phenyl and (B) the pharmaceutically acceptable acid addition and quaternary ammonium salts thereof.
Claim 3
Dependent Claim
18 words
A compound as claimed in claim 1 which is 4-(4-Benazmidopiperid-1-yl)-1,1-(di-p-fluorophenyl)but-1-ene or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
18 words
A compound as claimed in claim 1, which is 4-(4-benzamidopiperid-1-yl)-1,1-diphenylbut-1-ene or a pharmaceutically acceptable acid addition salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-06-06 | 1980-12-06 | 1981-06-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-06-06 | 1984-12-06 | 1985-06-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-06-06 | 1988-12-06 | 1989-06-07 | $7700.00 | Window Closed / Lapsed |