US4027017A
Expired / Lapsed
US
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Method of treating alcoholism
Assignee: Chugai Pharmaceutical Co Ltd
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Filing: 1975-07-07
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Granted: 1977-05-31
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Expires: 1995-07-07
Abstract
Abstract A pharmaceutical composition for treating alcoholism containing a uridine diphosphate glucuronic acid as an effective ingredient and a method of the use thereof are disclosed.
Inventors
- 👤 Shun-ichi Hata
- 👤 Koji Mizuno
- 👤 Yasuho Nishii
- 👤 Etsuko Mitsuishi
- 👤 Motoharu Shiba
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:28
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
70 words
A method of reducing the alcohol content of the blood and the accumulation of neutral lipids in the liver following the intake of alcoholic drinks, which comprises orally administering to a patient in need of said therapy a pharmaceutical composition comprising an effective amount of a uridine diphosphate glucuronic acid as an active ingredient, and a pharmaceutically acceptable carrier, just before or at the time of intake of alcoholic drinks.
Claim 2
Independent Claim
70 words
A method of reducing the alcohol content of the blood and the accumulation of neutral lipids in the liver following the intake of alcoholic drinks, which comprises orally administering to a patient in need of said therapy a pharmaceutical composition comprising an effective amount of a uridine diphosphate glucuronic acid as an active ingredient, and a pharmaceutically acceptable carrier, just before or at the time of intake of alcoholic drinks.
Claim 3
Dependent Claim
23 words
A method as set forth in claim 1 wherein said uridine diphosphate glucuronic acid is uridine-5'-diphosphate glucuronic acid or a metallic salt thereof.
Claim 4
Dependent Claim
24 words
A method as set forth in claim 2 wherein said metallic salt is selected from the group consisting of sodium, potassium and lithium salts.
Claim 5
Dependent Claim
23 words
A method as set forth in claim 1 wherein said uridine diphosphate glucuronic acid is uridine-3'-diphosphate glucuronic acid or a metallic salt thereof.
Claim 6
Dependent Claim
24 words
A method as set forth in claim 4 wherein said metallic salt is selected from the group consisting of sodium, potassium and lithium salts.
Claim 7
Dependent Claim
24 words
A method as set forth in claim 1 wherein said pharmaceutical composition is in a form of tablet, granule, powder, capsule, suspension or lemonade.
Claim 8
Dependent Claim
28 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate glucuronic acid is made in a dose of from 50 to 7,000 mg.
Claim 9
Dependent Claim
28 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate glucuronic acid is made in a dose of from 100 to 700 mg.
Claim 10
Dependent Claim
36 words
A method as set forth in claim 1 wherein said pharmaceutical composition is adminstered several times a day the total amount per day being a maximum of 400 mg/kg. body weight based on the active ingredient.
Claim 11
Independent Claim
79 words
A method of reducing the alcohol content of the blood and the accumulation of neutral lipids in the liver following the intake of alcoholic drinks, which comprises intravenously or intramuscularly injecting in a patient in need of such therapy a pharmaecutical composition in the form of a parenteral injection comprising an effective amount of a uridine diphosphate glucuronic acid as an active ingredient and a pharmaceutically acceptable carrier, just before or at the time of intake of alcoholic drinks.
Claim 12
Independent Claim
79 words
A method of reducing the alcohol content of the blood and the accumulation of neutral lipids in the liver following the intake of alcoholic drinks, which comprises intravenously or intramuscularly injecting in a patient in need of such therapy a pharmaecutical composition in the form of a parenteral injection comprising an effective amount of a uridine diphosphate glucuronic acid as an active ingredient and a pharmaceutically acceptable carrier, just before or at the time of intake of alcoholic drinks.
Claim 13
Dependent Claim
28 words
A method as set forth in claim 10 wherein the administration of said uridine diphosphate glucuronic acid is made in a dose of from 50 to 1,500 mg.
Claim 14
Dependent Claim
28 words
A method as set forth in claim 10 wherein the administration of said uridine diphosphate glucuronic acid is made in a dose of from 100 to 700 mg.
Claim 15
Dependent Claim
23 words
A method as set forth in claim 10 wherein the uridine diphosphate glucuronic acid is uridine-5'-diphosphate glucuronic acid or a metallic salt thereof.
Claim 16
Dependent Claim
28 words
A method as set forth in claim 13 wherein said metallic salt of uridine-5'-diphosphate glucuronic acid is selected from the group consisting of sodium, potassium and lithium salts.
Claim 17
Dependent Claim
23 words
A method as set forth in claim 10 wherein the uridine diphosphate glucuronic acid is uridine-3'-diphosphate glucuronic acid or a metallic salt thereof.
Claim 18
Dependent Claim
28 words
A method as set forth in claim 15 wherein said metallic salt of uridine-3'-diphosphate glucuronic acid is selected from the group consisting of sodium, potassium and lithium salts.
Claim 19
Dependent Claim
36 words
A method as set forth in claim 10 wherein said pharmaceutical composition is administered several times a day the total amount per day being a maximum of 40 mg/kg. body weight based on the active ingredient.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-30 | 1980-11-29 | 1981-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-30 | 1984-11-29 | 1985-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-30 | 1988-11-29 | 1989-05-31 | $7700.00 | Window Closed / Lapsed |