US4026879A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antigen-containing propranolol derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1976-03-23
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Granted: 1977-05-31
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Expires: 1996-03-23
Abstract
Abstract New hapten compositions useful in preparing antigens which may be employed in eliciting antibodies useful in immunoassay, particularly radioimmunoassay for propranolol. Utilizing an enantiomer in formation of the hapten allows preparation of an antibody which is able to discriminate between enantiomers selectively.
Inventors
- 👤 Sidney Spector
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 10:49
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/94; G01N33/9453; C; C07; C07K; C07K16/00; C07K16/44; Y; Y10; Y10S; Y10S436/00; Y10S436/815; Y10S436/823; Y10S530/00; Y10S530/806; Y10S530/807
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
35 words
An antigen consisting essentially of a propranolol hapten of the formula ##STR14## wherein n is an integer from 2 to 6; said hapten being convalently bonded to an immunogenic carrier material through the carboxyl group.
Claim 2
Dependent Claim
35 words
An antigen consisting essentially of a propranolol hapten of the formula ##STR14## wherein n is an integer from 2 to 6; said hapten being convalently bonded to an immunogenic carrier material through the carboxyl group.
Claim 3
Dependent Claim
14 words
The antigen of claim 1 wherein said immunogenic carrier material is bovine serum albumin.
Claim 4
Dependent Claim
10 words
The antigen of claim 1 wherein said n is 2.
Claim 5
Dependent Claim
14 words
The antigen of claim 3 wherein the propranolol of said hapten is the 1-enantiomer.
References Cited (Backward Citations)
US3690834A
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US3704282A
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US3852157A
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US3975342A
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US3878187A
Cited
US3988430A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-30 | 1980-11-29 | 1981-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-30 | 1984-11-29 | 1985-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-30 | 1988-11-29 | 1989-05-31 | $7700.00 | Window Closed / Lapsed |