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US4021117A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for automatic counting and measurement of particles

Assignee: Individual
•
Filing: 1975-08-07
•
Granted: 1977-05-03
•
Expires: 1995-08-07
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Abstract

Abstract A method of counting and analyzing pulses representative of characteristics of particles passing through a detector device including detecting the amplitude of each pulse, measuring the area under each pulse and above a reference level, deriving a ratio of amplitude to measured area, and determining which pulses have a ratio over a selected threshold as an indication of simultaneous passage of more than one pulse through the sensing zone of the detector device.

Inventors

  • 👤 Hildegard Gohde
  • 👤 Wolfgang Gohde

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 18:38
CPC Classifications
G; G01; G01N; G01N15/00; G01N15/10; G01N15/14; G01N15/1456; G01N15/1031; G01N15/12; G01N15/131; G01N15/132; G01N2015/1019

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 109 words
A method of automatic counting and measurement of particles, especially biological cells, suspended in a fluid medium, comprising passing the medium and the particles suspended therein through a physically defined zone; producing electrical signals having amplitudes and durations representative of characteristics of the particles passing through the zone; measuring the maximum amplitude of each of the signals; measuring the area under each of the signals and greater than a preselected level; determining the ratio of the measurements of maximum amplitude to area; and identifying those signals for which the ratio exceeds a predetermined value as being indicative of the coincidental passage of more than one particle through said zone.
Claim 2
Independent Claim 109 words
A method of automatic counting and measurement of particles, especially biological cells, suspended in a fluid medium, comprising passing the medium and the particles suspended therein through a physically defined zone; producing electrical signals having amplitudes and durations representative of characteristics of the particles passing through the zone; measuring the maximum amplitude of each of the signals; measuring the area under each of the signals and greater than a preselected level; determining the ratio of the measurements of maximum amplitude to area; and identifying those signals for which the ratio exceeds a predetermined value as being indicative of the coincidental passage of more than one particle through said zone.
Claim 3
Dependent Claim 32 words
A method according to claim 1, particularly for counting of blood corpuscles, wherein signals representative of coincidences are counted separately from the counting of all signals and the two counts are summed.
Claim 4
Dependent Claim 24 words
A method according to claim 1 wherein the electrical signals are produced from pulses of light produced by particles passing through a pulse cytophotometer.
Claim 5
Dependent Claim 21 words
A process according to claim 1 wherein the electrical signals are produced by passing the particles through a capacitance sensing device.
Claim 6
Dependent Claim 21 words
A process according to claim 1 wherein the electrical signals are produced by passing the particles through a resistivity sensing device.

References Cited (Backward Citations)

US3861800A Cited
US3936741A Cited
US3938038A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-05-02 1980-11-01 1981-05-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-05-02 1984-11-01 1985-05-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-05-02 1988-11-01 1989-05-03 $7700.00 Window Closed / Lapsed

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