Silicone composition for analyzing blood samples

Claim 1

A blood analysis composition comprising a small but effective amount of blood necessary for laboratory analysis and a small but effective amount of blood-separating composition having controlled rheological properties and a specific gravity that varies from 1.035 to 1.06 wherein said composition comprises (a) 100 parts by weight of a diorganopolysiloxane and blends of such polysiloxanes which are compatible with each other of a viscosity varying from 10,000 to 500,000 centipoise at 25° C, where the organo groups are selected from the group consisting of methyl, phenyl, chlorophenyl and mixtures thereof; (b) from 3 to 50 parts by weight of a filler selected from the group consisting of fumed silica and fumed silica treated with a silicone compound wherein the amount of treated fumed silica varies from 0 to 100% by weight of the total silica present; and (c) from 0.05 to 3 parts by weight of a stablizing compound of the formula, R'O (C.sub.a H.sub.2a O).sub.x (C.sub.b H.sub.2b O).sub.y H where R' is a member selected from the group consisting of hydrogen and lower alkyl radicals having from 1 to 7 carbon atoms, a and b are integers equal to from 1 to 4 inclusive, x is an integer equal to from 4 to 50 or more, and y is a whole number equal to from 0 to 50.

Claim 9

A method for analyzing a blood sample composed of blood serum and blood clots in part comprising adding to said blood sample a small but effective amount of blood-separating composition having controlled rheological properties and a specific gravity that varies from 1.035 to 1.06 wherein said composition comprises (a) 100 parts by weight of a diorganopolysiloxane and blends of such diorganopolysiloxanes which are compatible with each other of a viscosity varying from 10,000 to 500,000 centipoise at 25° C where the organo groups are selected from the group consisting of methyl, phenyl, chlorophenyl and mixtures thereof; (b) from 3 to 50 parts by weight of a filler selected from the group consisting of a fumed silica and fumed silica treated with a silicone compound wherein the amount of treated fumed silica varies from 0 to 100% by weight of the total silica present; and (c) from 0.05 to 3 parts by weight of a stablizing compound of the formula, R'O (C.sub.a H.sub.2a O).sub.x (C.sub.b H.sub.2b O).sub.y H where R' is a member selected from the group consisting of hydrogen and lower alkyl radicals having from 1 to 7 carbon atoms, a and b are integers equal to from 1 to 4 inclusive, x is an integer equal to from about 4 to 5 or more and y is a whole number equal to from 0 to 50; and centrifuging the blood sample and said blood-separating composition to separate said blood serum from said blood clots with said blood-separating composition forming an integral barrier between said blood clots and said blood serum.

Claim 10

A method for analyzing a blood sample composed of blood serum and blood clots in part comprising adding to said blood sample a small but effective amount of blood-separating composition having controlled rheological properties and a specific gravity that varies from 1.035 to 1.06 wherein said composition comprises (a) 100 parts by weight of a diorganopolysiloxane and blends of such diorganopolysiloxanes which are compatible with each other of a viscosity varying from 10,000 to 500,000 centipoise at 25° C where the organo groups are selected from the group consisting of methyl, phenyl, chlorophenyl and mixtures thereof; (b) from 3 to 50 parts by weight of a filler selected from the group consisting of a fumed silica and fumed silica treated with a silicone compound wherein the amount of treated fumed silica varies from 0 to 100% by weight of the total silica present; and (c) from 0.05 to 3 parts by weight of a stablizing compound of the formula, R'O (C.sub.a H.sub.2a O).sub.x (C.sub.b H.sub.2b O).sub.y H where R' is a member selected from the group consisting of hydrogen and lower alkyl radicals having from 1 to 7 carbon atoms, a and b are integers equal to from 1 to 4 inclusive, x is an integer equal to from about 4 to 5 or more and y is a whole number equal to from 0 to 50; and centrifuging the blood sample and said blood-separating composition to separate said blood serum from said blood clots with said blood-separating composition forming an integral barrier between said blood clots and said blood serum.