US4016255A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral hygiene compositions
Assignee: Beecham Group PLC
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Filing: 1975-09-11
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Granted: 1977-04-05
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Expires: 1995-09-11
Abstract
Abstract Oral hygiene anti-cariogenic compositions comprising a water-soluble fluoride compound and a potentiating amount of a water-soluble ammonium compound in molar ionic ratio ranges of 1.2:1 or greater, the ammonium compound not being a condensation product of ammonia and phosphorus pentoxide, the acid-solubility of dental enamel decreasing with increasing ammonium content.
Inventors
- 👤 Geoffrey Charles Forward
- 👤 Susan Ann Duke
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:08
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/55; A61K8/19; A61K8/20; A61K8/21; A61Q; A61Q11/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
69 words
An oral hygiene composition comprising a physiologically acceptable water-soluble fluoride compound selected from sodium fluoride, potassium fluoride, ammonium fluoride, stannous fluoride, sodium monofluorophosphate and mixtures thereof and a physiologically acceptable water-soluble ammonium compound selected from ammonium chloride, ammonium bromide, ammonium sulfate, ammonium triphosphate, ammonium dihydrogen phosphate, diammonium hydrogen phospate and mixtures thereof, the molar ratio of available ammonium ion to available fluoride in said composition being 1.2:1 or greater.
Claim 2
Dependent Claim
69 words
An oral hygiene composition comprising a physiologically acceptable water-soluble fluoride compound selected from sodium fluoride, potassium fluoride, ammonium fluoride, stannous fluoride, sodium monofluorophosphate and mixtures thereof and a physiologically acceptable water-soluble ammonium compound selected from ammonium chloride, ammonium bromide, ammonium sulfate, ammonium triphosphate, ammonium dihydrogen phosphate, diammonium hydrogen phospate and mixtures thereof, the molar ratio of available ammonium ion to available fluoride in said composition being 1.2:1 or greater.
Claim 3
Dependent Claim
40 words
A composition as claimed in claim 1 wherein the said fluoride compound is a mixture of sodium fluoride and sodium monofluorophosphate in amounts such that from 40 to 80% of the total fluoride content is provided by the sodium fluoride.
Claim 4
Dependent Claim
15 words
A composition as claimed in claim 1 which includes ammonium fluoride, ammonium monofluorophosphate or both.
Claim 5
Dependent Claim
23 words
A composition as claimed in claim 1 wherein the molar ratio of available ammonium ion to available fluoride is from 1.2:1 to 20:1.
Claim 6
Dependent Claim
15 words
A composition as claimed in claim 4 wherein said ratio is from 2:1 to 20:1.
Claim 7
Dependent Claim
15 words
A composition as claimed in claim 4 wherein said ratio is from 5:1 to 15:1.
Claim 8
Dependent Claim
15 words
A composition as claimed in claim 4 wherein said ratio is from 8:1 to 15:1.
Claim 9
Dependent Claim
15 words
A composition as claimed in claim 4 wherein said ratio is from 8:1 to 12:1.
Claim 10
Dependent Claim
13 words
A composition as claimed in claim 4 wherein said ratio is about 10:1.
Claim 11
Dependent Claim
18 words
A composition as claimed in claim 1 formulated as a mouthwash, toothpaste, dental cream, toothpowder or chewing gum.
Claim 12
Dependent Claim
20 words
A composition as claimed in claim 1 formulated as a mouthwash containing from 10 to 1000 ppm of available fluoride.
Claim 13
Dependent Claim
16 words
A mouthwash as claimed in claim 11 containing from 50 to 250 ppm of available fluoride.
Claim 14
Dependent Claim
20 words
A composition as claimed in claim 1 formulated as a toothpaste containing from 100 to 2500 ppm of available fluoride.
Claim 15
Dependent Claim
16 words
A toothpaste as claimed in claim 13 containing from 750 to 1,500 ppm of available fluoride.
Claim 16
Dependent Claim
14 words
A toothpaste as claimed in claim 13 containing about 1000 ppm of available fluoride.
References Cited (Backward Citations)
US2542518A
Cited
US2542886A
Cited
US2588324A
Cited
US2601238A
Cited
US2588992A
Cited
US2647073A
Cited
US2622058A
Cited
US3277118A
Cited
US3235459A
Cited
US3227618A
Cited
US3666855A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-04-04 | 1980-10-04 | 1981-04-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-04-04 | 1984-10-04 | 1985-04-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-04-04 | 1988-10-04 | 1989-04-05 | $7700.00 | Window Closed / Lapsed |