US4013820A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Universally useable tableting ingredients
Assignee: Abbott Laboratories
•
Filing: 1974-11-07
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Granted: 1977-03-22
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Expires: 1994-11-07
Abstract
Abstract Known polymers of a defined class are converted into a universally useable tableting ingredient that provides controlled release of a drug from tablets made with this material. The new material is made in a rapidly stirred, nonaqueous solvent in a one-step process.
Inventors
- 👤 Bahram Farhadieh
- 👤 James Maynard Berdahl
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 20:50
CPC Classifications
C; C08; C08L; C08L1/00; C08L1/08; C08L1/10; C08L1/14; A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/205; A61K9/2054; Y; Y10; Y10S; Y10S526/00; Y10S526/936
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
103 words
The process of making a powdered, controlled-release tableting medium of essentially unlimited shelf-life consisting essentially in dissolving a nontoxic polymeric film-forming material having repeating free carboxylic acid groups attached to the polymeric chain in a low boiling, substantially water-free organic liquid and combining this solution with a solution of ammonia, sodium hydroxide or potassium hydroxide in an alcohol of 1 - 3 carbon atoms under conditions of turbulence over a period of at least 15 minutes and separating the formed polymer salt from the liquid phase by a method which does not require exposing said polymer salt to an extended period of heat.
Claim 2
Dependent Claim
103 words
The process of making a powdered, controlled-release tableting medium of essentially unlimited shelf-life consisting essentially in dissolving a nontoxic polymeric film-forming material having repeating free carboxylic acid groups attached to the polymeric chain in a low boiling, substantially water-free organic liquid and combining this solution with a solution of ammonia, sodium hydroxide or potassium hydroxide in an alcohol of 1 - 3 carbon atoms under conditions of turbulence over a period of at least 15 minutes and separating the formed polymer salt from the liquid phase by a method which does not require exposing said polymer salt to an extended period of heat.
Claim 3
Dependent Claim
13 words
The process of claim 1 wherein said film-forming material is cellulose acetate phthalate.
Claim 4
Dependent Claim
13 words
The process of claim 1 wherein a solution of sodium hydroxide is used.
Claim 5
Dependent Claim
10 words
The process of claim 1 wherein said alcohol is ethanol.
Claim 6
Dependent Claim
61 words
A powdered, controlled-release tableting medium for pharmaceutical tablets consisting essentially of a film-forming, non-toxic polymeric material carrying in each repeating monomeric unit a carboxylic acid salt group selected from the group consisting of ammonium, potassium and sodium carboxylates, said powdered tableting medium being characterized in that it contains essentially no heat degradation product, no entrapped solvent and possessing essentially unlimited shelf-life.
Claim 7
Dependent Claim
61 words
A powdered, controlled-release tableting medium for pharmaceutical tablets consisting essentially of a film-forming, non-toxic polymeric material carrying in each repeating monomeric unit a carboxylic acid salt group selected from the group consisting of ammonium, potassium and sodium carboxylates, said powdered tableting medium being characterized in that it contains essentially no heat degradation product, no entrapped solvent and possessing essentially unlimited shelf-life.
References Cited (Backward Citations)
US2093463A
Cited
US2768161A
Cited
US2809191A
Cited
US2865898A
Cited
US2852508A
Cited
US3080294A
Cited
US3424842A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-03-21 | 1980-09-20 | 1981-03-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-03-21 | 1984-09-20 | 1985-03-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-03-21 | 1988-09-20 | 1989-03-22 | $7700.00 | Window Closed / Lapsed |