US4012576A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antibiotic complex Bu 2183
Assignee: Bristol Myers Co
•
Filing: 1975-10-30
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Granted: 1977-03-15
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Expires: 1995-10-30
Abstract
Abstract A novel aminoglycoside antibiotic complex designated herein as Bu-2183 is produced by fermentation of Pseudomonas sp. strain D946-B83, A.T.C.C. 31086. Complex Bu-2183 is known to consist of at least five components, said components being herein designated Bu-2183 A, A2, B, C and D. The complex and the individual aminoglycoside components Bu-2183 A, A2, and B are found to have a broad spectrum of antibacterial activity and are especially useful in inhibiting aminoglycoside-resistant organisms including Pseudomonas species.
Inventors
- 👤 Hiroshi Kawaguchi
- 👤 Koji Tomita
- 👤 Kei-Ichi Fujisawa
- 👤 Hiroshi Tsukiura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-10 02:19
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/02; C07H15/04; A; A61; A61P; A61P31/00; A61P31/04; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/874
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
15 words
The antibiotic Bu-2183 A of the formula ##STR6##or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
15 words
The antibiotic Bu-2183 A of the formula ##STR6##or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
14 words
A pharmaceutically acceptable acid addition salt of Bu-2183 A as defined in claim 1.
Claim 4
Dependent Claim
15 words
The antibiotic Bu-2183 B of the formula ##STR7##or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
15 words
The antibiotic Bu-2183 B of the formula ##STR7##or a pharmaceutically acceptable acid addition salt thereof.
Claim 6
Dependent Claim
14 words
A pharmaceutically acceptable acid addition salt of Bu-2183 B as defined in claim 3.
Claim 7
Dependent Claim
16 words
The antibiotic Bu-2183 A 2 of the formula ##STR8##or a pharmaceutically acceptable acid addition salt thereof.
Claim 8
Dependent Claim
16 words
The antibiotic Bu-2183 A 2 of the formula ##STR8##or a pharmaceutically acceptable acid addition salt thereof.
Claim 9
Dependent Claim
15 words
A pharmaceutically acceptable acid addition salt of Bu-2183 A 2 as defined in claim 5.
Claim 10
Dependent Claim
14 words
The aminoglycoside substance Bu-2183 D of the formula ##STR9##or an acid addition salt thereof.
Claim 11
Dependent Claim
14 words
The aminoglycoside substance Bu-2183 D of the formula ##STR9##or an acid addition salt thereof.
Claim 12
Dependent Claim
12 words
An acid addition salt of Bu-2183 D as defined in claim 7.
References Cited (Backward Citations)
US3647779A
Cited
US3795668A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-03-14 | 1980-09-13 | 1981-03-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-03-14 | 1984-09-13 | 1985-03-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-03-14 | 1988-09-13 | 1989-03-15 | $7700.00 | Window Closed / Lapsed |