US4010252A
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US
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Antimicrobial compositions
Assignee: Colgate Palmolive Co
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Filing: 1974-12-19
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Granted: 1977-03-01
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Expires: 1994-12-19
Abstract
Abstract There is disclosed antimicrobial compositions based upon the combination of an antimicrobially effective poly (quaternary ammonium) compound and an antimicrobially effective simple anionic component. There is also disclosed methods of making the same and products made therefrom.
Inventors
- 👤 Gordon Trent Hewitt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 06:16
CPC Classifications
A; A61; A61Q; A61Q15/00; A01; A01N; A01N33/00; A01N33/02; A01N33/12; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/347; A61K8/72; A61K8/84; C; C11; C11D; C11D1/00; C11D1/38; C11D1/62; C11D3/00; C11D3/0005; C11D3/0068; C11D3/48; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5426
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
416 words
An antimicrobial composition comprising the product resulting from admixing (1) a compound selected from the group consisting of a poly (quaternary ammonium) compound having the formula ##STR14##wherein n is about 2-200, A is the anion of an acid, and R 1 and R 4 are polymethylene containing 6 to 20 carbon atoms and R 2 , R 3 , R 5 and R 6 are alkyl containing 1 to 3 carbon atoms ##STR15##wherein n = 10 2 to 5×10 3 ; R is alkyl containing 6 to 15 carbon atoms, x is halide metho-sulfate or etho-sulfate and (2) at least one compound selected from the group consisting of compounds having the formula ##STR16##wherein Y is hydrogen or hydroxy and X halogen, --CF 3 or --H, ##STR17##wherein R is a substituent selected from the group consisting of methyl and phenyl, each X is at least one of bromine and chlorine, y is 0 or 1, and m is an integer of about 1 to 5 (5-y), inclusive; ##STR18##wherein X represents a halogen such as chlorine or bromine, n represents an integer of about 1 to 3, and R represents S or a divalent alkylene radical having about 1 to 4 carbon atoms; ##STR19##wherein X represents a halogen such as chlorine or bromine, n is an integer of about 1 to 3, R is an alkyl group containing about 1 to 4 carbon atoms and Y is S or a divalent radical having about 1 to 4 carbon atoms; ##STR20##wherein each X 1 represents hydrogen or halogen, X 2 represents a halogen, and Y represents hydrogen, halogen or trifluoromethyl; ##STR21##wherein Q represents a member selected from the group consisting of hydrogen, chlorine, bromine, and iodine, X 1 and X 2 each represent a member selected from the group consisting of hydrogen, chlorine, bromine, iodine and CH 3 , X 3 represents a member selected from the group consisting of hydrogen, chlorine, bromine and CH 3 and X 4 and Y each represent a member selected from the group consisting of hydrogen, chlorine and bromine, there being at least two halogen substituents in the X positions; ##STR22##wherein X is chlorine, bromine or iodine and n is 0 to about 1; ##STR23##wherein X is chlorine, bromine, iodine or hydrogen and a is 0 to about 2, with the proviso that there is at least one and not more than three directly attached halogen atoms, none of which is adjacent to any of the others or to the CF 3 group.
Claim 2
Dependent Claim
416 words
An antimicrobial composition comprising the product resulting from admixing (1) a compound selected from the group consisting of a poly (quaternary ammonium) compound having the formula ##STR14##wherein n is about 2-200, A is the anion of an acid, and R 1 and R 4 are polymethylene containing 6 to 20 carbon atoms and R 2 , R 3 , R 5 and R 6 are alkyl containing 1 to 3 carbon atoms ##STR15##wherein n = 10 2 to 5×10 3 ; R is alkyl containing 6 to 15 carbon atoms, x is halide metho-sulfate or etho-sulfate and (2) at least one compound selected from the group consisting of compounds having the formula ##STR16##wherein Y is hydrogen or hydroxy and X halogen, --CF 3 or --H, ##STR17##wherein R is a substituent selected from the group consisting of methyl and phenyl, each X is at least one of bromine and chlorine, y is 0 or 1, and m is an integer of about 1 to 5 (5-y), inclusive; ##STR18##wherein X represents a halogen such as chlorine or bromine, n represents an integer of about 1 to 3, and R represents S or a divalent alkylene radical having about 1 to 4 carbon atoms; ##STR19##wherein X represents a halogen such as chlorine or bromine, n is an integer of about 1 to 3, R is an alkyl group containing about 1 to 4 carbon atoms and Y is S or a divalent radical having about 1 to 4 carbon atoms; ##STR20##wherein each X 1 represents hydrogen or halogen, X 2 represents a halogen, and Y represents hydrogen, halogen or trifluoromethyl; ##STR21##wherein Q represents a member selected from the group consisting of hydrogen, chlorine, bromine, and iodine, X 1 and X 2 each represent a member selected from the group consisting of hydrogen, chlorine, bromine, iodine and CH 3 , X 3 represents a member selected from the group consisting of hydrogen, chlorine, bromine and CH 3 and X 4 and Y each represent a member selected from the group consisting of hydrogen, chlorine and bromine, there being at least two halogen substituents in the X positions; ##STR22##wherein X is chlorine, bromine or iodine and n is 0 to about 1; ##STR23##wherein X is chlorine, bromine, iodine or hydrogen and a is 0 to about 2, with the proviso that there is at least one and not more than three directly attached halogen atoms, none of which is adjacent to any of the others or to the CF 3 group.
Claim 3
Dependent Claim
35 words
A composition as defined in claim 1 wherein component (2) has the formula ##STR24##wherein R is --CH 2 , S or O, X is halogen, n is about 1-3 and Y is H or --OH.
Claim 4
Dependent Claim
15 words
A composition as defined in claim 1 wherein component (2) is te formula VIII compound.
Claim 5
Dependent Claim
15 words
A composition as defined in claim 1 wherein component (2) is the formula IV compound.
Claim 6
Dependent Claim
15 words
A composition as defined in claim 1 wherein component (2) is the formula VI compound.
Claim 7
Dependent Claim
24 words
A composition as defined in claim 1 wherein about 1 mole of component (2) is employed for about each 1 equivalent of component (1).
Claim 8
Dependent Claim
21 words
A composition as defined in claim 1 wherein component (1) has a molecular weight of at about 5,000 to about 40,000.
Claim 9
Dependent Claim
69 words
A composition as defined in claim 1 wherein component (1) has repeating units of the formula: ##STR25##wherein R is a normal or branched chain alkylene group having about 6 to 16 carbon atoms, R 1 and R 2 is CH 3 , C 2 H 5 , or C 2 H 4 OH, and X is R, C1, Br, I, OSO 3 CH 3 , or CH 3 COO.
Claim 10
Dependent Claim
36 words
A composition as defined in claim 8 wherein, in the formula for said repeating units, R is (CH 2 ) 10 , R 1 and R 2 are each CH 3 , and X is Br.
Claim 11
Dependent Claim
48 words
A deodorant composition comprising a liquid medium comprising at least one member selected from the group consisting of water, alcohol, and a liquified normally gaseous propellant and containing an antimicrobially effective amount ranging from about 0.02 to 3.05 by weight of a composition as defined in claim 1.
Claim 12
Dependent Claim
14 words
A deodorant composition as defined in claim 10 wherein said liquid medium contains water.
Claim 13
Dependent Claim
14 words
A deodorant composition as defined in claim 10 wherein said liquid medium contains alcohol.
Claim 14
Dependent Claim
18 words
A deodorant composition as defined in claim 10 wherein said liquid medium contains a liquified normally gaseous propellant.
Claim 15
Dependent Claim
51 words
A deodorant composition as defined in claim 10 wherein said liquid medium also contains about 0.5 to 15% by weight of a powdered astringent antisperspirant material selected from the group consisting of salts and complexes of zirconium, zinc, aluminum, and iron which are insoluble in alcohol and liquified normally gaseous propellants.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-02-29 | 1980-08-30 | 1981-03-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-02-29 | 1984-08-30 | 1985-03-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-02-29 | 1988-08-30 | 1989-03-01 | $7700.00 | Window Closed / Lapsed |