8-Carboxylester, and 8-carbamyl derivitives of 5,6,7,8-tetrahydroquinoline

Claim 1

A compound of formula I l ##STR11## and acid addition salts thereof with pharmaceutically acceptable acids, wherein R 1 , R 2 and R 6 are the same or different and are selected from hydrogen, alkyl containing from 1 to 6 carbon atoms, phenylalkyl wherein the alkyl group has 1-6 carbon atoms, or phenyl groups or R 1 and R 2 taken together represent a polymethylene chain of 3 to 5 carbon atoms, R 7 represents hydrogen, alkyl of 1 to 6 carbon atoms or gem di n-alkyl of 1-6 carbon atoms, phenylalkyl wherein the alkyl group has 1 to 6 carbon atoms or phenyl, X is CONHR 3 or CO 2 R 5 wherein R 3 is hydrogen or alkyl of 1 to 6 carbon atoms, and R 5 is hydrogen, alkyl of 1 to 6 carbon atoms or phenylalkyl wherein the alkyl group has 1 to 6 carbon atoms and metal salts of the compounds wherein X is CO.sub. 2 R 5 and R 5 is hydrogen with the proviso that when R 1 and R 2 or R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups