Process for alleviating proliferative skin diseases

Claim 1

A process for treating proliferating skin diseases which comprises administering to the afflicted human or animal, a composition containing as an active component at least one of the compounds selected from the groups: I. A compound of the formula ##STR5## wherein R 1 is H or methyl; R 2 is H or phenyl; R 3 is propyl, isopropyl or phenyl; R 4 is H, bromine, methylthio, or benzylthio; X is oxygen or methylene; Ii. a compound of the formula ##STR6## wherein R 1 and R 2 are hydrogen or hydroxyl; Y is hydrogen or alkali metal; Z is hydrogen, benzylthio, thiol, halogen, alkylthio wherein alkyl is from 1 to 8 carbon atoms, inclusive, and hydroxy; R 4 is hydrogen, ##STR7## wherein R 5 is phenyl, benzyl or alkyl of 1 to 8 carbon atoms; III. A compound of the formula ##STR8## wherein R 1 is --CONH 2 , --CSNH 2 , --C(NH)NH 2 , --C(NH)NHOH, --CN, or --COOCH 3 ; R 1 and R 2 are hydrogen or hydroxy; Y is hydrogen or alkali metal, said compounds being in association with a pharmaceutical carrier wherein the concentration of said active component is effective to alleviate a proliferative skin disease.