US4003792A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Conjugates of acid polysaccharides and complex organic substances
Assignee: Bayer Corp
•
Filing: 1972-08-08
•
Granted: 1977-01-18
•
Expires: 1992-08-08
Abstract
Abstract This invention relates to chemical conjugates of acid polysaccharides and biochemically active complex organic molecules and particularly to such conjugates which are capable of forming soluble sodium salts and insoluble calcium salts.
Inventors
- 👤 Patrick James Mill
- 👤 Michael Alan Cresswell
- 👤 Joseph George Feinberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:18
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0045; A; A61; A61K; A61K36/00; A61K36/06; A61K36/062; A61K36/064; A61K39/00; A61K39/385; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/61; C12; C12N; C12N11/00; C12N11/02; C12N11/10; A61K2039/60; A61K2039/6031; A61K2039/6037; A61K2039/6087; Y; Y10; Y10S; Y10S530/00; Y10S530/81; Y10S530/812; Y10S530/813; Y10S530/82; Y10S530/822; Y10S530/827; Y10S530/842; Y10S530/855; Y10S530/857
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
133 words
An immunologically active conjugate capable of forming soluble sodium salts and insoluble calcium salts comprising: an acid polysaccharide selected from the group consisting of pectin, pectic acid, alginic acid, celluronic acid, lichenin uronic acid, and carrageenan and comprising from about 93 to 98% of said conjugate, which polysaccharide is bonded covalently by a linkage selected from the group consisting of amide, ester, and a combination of amide and ester bonds to an immunologically active proteinaceous component selected from the group consisting of ovalbumin, lactalbumin, insulin, trypsin, chymotrypsin, ficin, Timothy pollen extract, cocksfoot pollen extract, ragweed pollen extract, birch pollen extract, horse dander extract, cat epithelium extract, haddock extract, dry rot extract, baker's yeast extract, tetanus toxoid, diptheria toxin, bee venom, and snake venom and comprising from about 2 to 7% of said conjugate.
Claim 2
Dependent Claim
133 words
An immunologically active conjugate capable of forming soluble sodium salts and insoluble calcium salts comprising: an acid polysaccharide selected from the group consisting of pectin, pectic acid, alginic acid, celluronic acid, lichenin uronic acid, and carrageenan and comprising from about 93 to 98% of said conjugate, which polysaccharide is bonded covalently by a linkage selected from the group consisting of amide, ester, and a combination of amide and ester bonds to an immunologically active proteinaceous component selected from the group consisting of ovalbumin, lactalbumin, insulin, trypsin, chymotrypsin, ficin, Timothy pollen extract, cocksfoot pollen extract, ragweed pollen extract, birch pollen extract, horse dander extract, cat epithelium extract, haddock extract, dry rot extract, baker's yeast extract, tetanus toxoid, diptheria toxin, bee venom, and snake venom and comprising from about 2 to 7% of said conjugate.
Claim 3
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is ovalbumin.
Claim 4
Dependent Claim
22 words
A conjugate is recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is Timothy pollen extract.
Claim 5
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is cocksfoot pollen extract.
Claim 6
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is birch pollen extract.
Claim 7
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is horse dander extract.
Claim 8
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is cat opithelial extract.
Claim 9
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is haddock extract.
Claim 10
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is dry rot extract.
Claim 11
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is baker's yeast extract.
Claim 12
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is snake venom.
Claim 13
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is bee venom.
Claim 14
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is diptheria toxin.
Claim 15
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is tetanus toxoid.
Claim 16
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is lactalbumin.
Claim 17
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is insulin.
Claim 18
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is trypsin.
Claim 19
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is chymotrypsin.
Claim 20
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is alginic acid and said active component is ficin.
Claim 21
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectic acid and said active component is ovalbumin.
Claim 22
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectic acid and said active component is ragweed pollen extract.
Claim 23
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectic acid and said active component is Timothy pollen extract.
Claim 24
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectic acid and said active component is cocksfoot pollen extract.
Claim 25
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectin and said active component is Timothy pollen extract.
Claim 26
Dependent Claim
19 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectin and said active component is ovalbumin.
Claim 27
Dependent Claim
19 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectin and said active component is chymotrypsin.
Claim 28
Dependent Claim
19 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is pectin and said active component is trypsin.
Claim 29
Dependent Claim
20 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is celluronic acid and said active component is ovalbumin.
Claim 30
Dependent Claim
22 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is celluronic acid and said active component is Timothy pollen extract.
Claim 31
Dependent Claim
19 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is carrageenan and said active component is ovalbumin.
Claim 32
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is carrageenan and said active component is Timothy pollen extract.
Claim 33
Dependent Claim
21 words
A conjugate as recited in claim 1 wherein said acid polysaccharide is lichenin uronic acid and said active component is ovalbumin.
References Cited (Backward Citations)
GB1174854A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-01-18 | 1980-07-19 | 1981-01-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-01-18 | 1984-07-19 | 1985-01-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-01-18 | 1988-07-19 | 1989-01-18 | $7700.00 | Window Closed / Lapsed |