US4000260A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti herpes simplex viral compounds and their synthesis
Assignee: Research Corp
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Filing: 1975-08-15
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Granted: 1976-12-28
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Expires: 1995-08-15
Abstract
Abstract The compounds 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine; and the pharmaceutically acceptable acid addition salts thereof have been found to be potent inhibitors of herpes simplex virus.
Inventors
- 👤 H. William Prusoff
- 👤 Yung-Chi Cheng
- 👤 David C. Ward
- 👤 John P. Neenan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:50
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
18 words
A compound selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine; and the pharmaceutically acceptable acid addition salts thereof.
Claim 2
Dependent Claim
18 words
A compound selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine; and the pharmaceutically acceptable acid addition salts thereof.
Claim 3
Dependent Claim
1 words
5'-Amino-2',5'-dideoxy-5-iodouridine.
Claim 4
Dependent Claim
1 words
5'-Amino-2',5'-dideoxy-5-iodouridine.
Claim 5
Dependent Claim
1 words
5'-Amino-2',5'-dideoxy-5-bromouridine.
Claim 6
Dependent Claim
1 words
5'-Amino-2',5'-dideoxy-5-bromouridine.
Claim 7
Dependent Claim
43 words
A pharmaceutical composition containing an effective amount of a compound for treating herpes simplex virus infection in mammals, said compound being selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine and the pharmaceutically acceptable acid addition salts thereof together with a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim
43 words
A pharmaceutical composition containing an effective amount of a compound for treating herpes simplex virus infection in mammals, said compound being selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine; 5'-amino-2',5'-dideoxy-5-bromouridine and the pharmaceutically acceptable acid addition salts thereof together with a pharmaceutically acceptable carrier.
Claim 9
Dependent Claim
7 words
A composition of claim 4 containing 5'-amino-2',5'-dideoxy-5-iodouridine.
Claim 10
Dependent Claim
7 words
A composition of claim 4 containing 5'-amino-2',5'-dideoxy-5-bromouridine.
Claim 11
Independent Claim
57 words
A method of treating a herpes simplex virus infection in a host mammal afflicted with such infection which comprises administering to the said host an amount of a compound which is effective for treating a herpes simplex virus infection, said compound being selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine, 5'-amino-2',5'-dideoxy-5-bromouridine and the pharmaceutically acceptable acid salts thereof.
Claim 12
Independent Claim
57 words
A method of treating a herpes simplex virus infection in a host mammal afflicted with such infection which comprises administering to the said host an amount of a compound which is effective for treating a herpes simplex virus infection, said compound being selected from the group consisting of 5'-amino-2',5'-dideoxy-5-iodouridine, 5'-amino-2',5'-dideoxy-5-bromouridine and the pharmaceutically acceptable acid salts thereof.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-12-28 | 1980-06-28 | 1980-12-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-12-28 | 1984-06-28 | 1984-12-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-12-28 | 1988-06-28 | 1988-12-28 | $7700.00 | Window Closed / Lapsed |