US4000129A
Expired / Lapsed
US
⏱️ 0.0 years remaining
6-aminopenicillanic acid sulfoxide silyl esters
Assignee: DSM Delft BV
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Filing: 1974-08-26
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Granted: 1976-12-28
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Expires: 1994-08-26
Abstract
Abstract Novel 6-substituted amino-penicillanic sulfoxide silyl esters useful as intermediates for the preparation of 7-aminodesacetoxycephalosporanic acids derivatives.
Inventors
- 👤 Jan Verweij
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 16:07
CPC Classifications
C; C07; C07D; C07D499/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
82 words
6-aminopenicillanic acid sulfoxide silyl esters of the formula ##STR4## wherein R is selected from the group consisting of benzyl, phenyl (amino-methylene), phenyl (benzyloxycarbamoyl-methylene), phenoxy methyl, naphthyl and ethoxy-naphthyl and Y 1 , Y 2 and Y 3 are individually selected from the group consisting of halogen, haloalkyl and alkyl of 1 to 4 carbon atom, phenyl and 6-substituted aminopenicillanyl sulfoxide carbonyloxy according to the group which is attached to the silicon atom in the above formula, wherein R is as hereinbefore defined.
Claim 2
Dependent Claim
82 words
6-aminopenicillanic acid sulfoxide silyl esters of the formula ##STR4## wherein R is selected from the group consisting of benzyl, phenyl (amino-methylene), phenyl (benzyloxycarbamoyl-methylene), phenoxy methyl, naphthyl and ethoxy-naphthyl and Y 1 , Y 2 and Y 3 are individually selected from the group consisting of halogen, haloalkyl and alkyl of 1 to 4 carbon atom, phenyl and 6-substituted aminopenicillanyl sulfoxide carbonyloxy according to the group which is attached to the silicon atom in the above formula, wherein R is as hereinbefore defined.
Claim 3
Dependent Claim
23 words
A 6-aminopenicillanic acid sulfoxide silyl ester of claim 1 wherein R is selected from the group consisting of benzyl, phenoxymethyl, α-benzyloxycarbamoyl-benzyl and 2-ethoxy-naphthyl.
Claim 4
Dependent Claim
31 words
A 6-aminopenicillanic acid sulfoxide silyl ester of claim 1 wherein Y 1 , Y 2 and Y 3 are selected from the group consisting of chlorine, methyl, chloromethyl, phenyl and butyl.
Claim 5
Dependent Claim
11 words
A compound of claim 1 which is 6-phenylacetamidopenicillanic sulfoxide trimethylsilyl ester.
Claim 6
Dependent Claim
11 words
A compound of claim 1 which is phenoxymethylpenicillin sulfoxide dimethylchlorosilyl ester.
Claim 7
Dependent Claim
10 words
A compound of claim 1 which is di(phenoxymethylpenicillinsulfoxide) dimethylsilyl ester.
Claim 8
Dependent Claim
13 words
A compound of claim 1 which is 6-(α-benzyloxycarbamoyl phenylacetamido) penicillin sulfoxide dimethylchlorosilyl ester.
Claim 9
Dependent Claim
13 words
A compound of claim 1 which is di [6-(α-benzyloxycarbamoyl-phenylacetamido) penicillin sulfoxide] dimethylsilyl ester.
Claim 10
Dependent Claim
12 words
A compound of claim 1 which is 2-ethoxy-naphthyl penicillin sulfoxide trimethylsilyl ester.
Claim 11
Dependent Claim
11 words
A compound of claim 1 which is phenoxymethylpenicillin sulfoxide trimethylsilyl ester.
Claim 12
Dependent Claim
12 words
A compound of claim 1 which is benzylpenicillin sulfoxide dimethyl(t-butyl) silyl ester.
Claim 13
Dependent Claim
11 words
A compound of claim 1 which is phenoxymethylpenicillin sulfoxide (dichloromethyl)dimethylsilyl ester.
Claim 14
Dependent Claim
11 words
A compound of claim 1 which is phenoxymethylpenicillin sulfoxide methyldiphenylsilyl ester.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-12-28 | 1980-06-28 | 1980-12-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-12-28 | 1984-06-28 | 1984-12-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-12-28 | 1988-06-28 | 1988-12-28 | $7700.00 | Window Closed / Lapsed |