Antibiotics

Claim 1

A compound selected from a base of the formula ##SPC14## wherein Aryl is selected from phenyl or 2-thienyl; Y is selected from hydrogen, chlorine, bromine, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or an alkoxy group of from 1 to 4 carbon atoms with the proviso that when Aryl is 2-thienyl, Y is hydrogen; each of R 1 , R 2 and R 3 is selected from hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms; Z is selected from a bond, oxygen, sulfur or imino with the proviso that when Aryl is 2-thienyl, Z is a bond; W is selected from hydrogen, methyl, anino, hydroxy, SO 3 H, or COOR 4 wherein R 4 is selected from hydrogen or 5-indanyl; n is zero, 1 or 2 with the proviso that when W is other than hydrogen or methyl and Z is other than a bond, n is not zero; R 5 is selected from hydrogen or methoxy; M is selected from hydrogen, a pharmaceutically acceptable non-toxic cation charge, an alkanoyloxymethyl group wherein the alkanoyl moiety has from 1 to 5 carbon atoms and may be straight or branched, an alkanoylaminomethyl group wherein the alkanoyl moiety has from 1 to 5 carbon atoms and may be straight or branched and wherein the amino nitrogen may be substituted with an alkyl group of from 1 to 4 carbon atoms, an alkoxycarbonylaminomethyl group wherein the alkoxy moiety has from 1 to 4 carbon atoms and may be straight or branched and wherein the amino nitrogen may be substituted with an alkyl group of from 1 to 4 carbon atoms, p-(alkanoyloxy)benzyl wherein the alkanoyl moiety contains from 1 to 5 carbon atoms and may be straight or branched or aminoalkanoyloxymethyl as represented by the group ##EQU1## wherein n' is 0 to 5, each of R 11 and R 12 is selected from hydrogen or lower alkyl of from 1 to 4 carbon atoms, and each of R 13 and R 14 is selected from hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms; and pharmaceutically acceptable salts thereof.