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US3992264A Expired / Lapsed US ⏱️ 0.0 years remaining

Antibiotic 1745A/X and methods for the production thereof

Assignee: Hoffmann La Roche Inc
•
Filing: 1975-07-23
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Granted: 1976-11-16
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Expires: 1995-07-23
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Abstract

Abstract A new antibiotic, designated as antibiotic 1745A/X, is produced by the fermentation of the known microorganism Streptomyces antibioticus, ATCC 11891, using the novel compound erythronolide A oxime as the substrate. This new antibiotic is useful as an antibacterial agent.

Inventors

  • 👤 Richard Wightman Kierstead
  • 👤 Ronald Andrew Le Mahieu
  • 👤 David Pruess

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 17:54
CPC Classifications
C; C07; C07D; C07D313/00; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/886; Y10S435/888

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 71 words
A process for the preparation of antibiotic 1745A/X which comprises cultivating Streptomyces antibiotics ATCC 11891, under submerged aerobic conditions, in an aqueous nutrient medium containing assimilable sources of carbohydrates, nitrogen and inorganic salts, to which has been added erythronolide A oxime as the substrate, until substantial antibiotic activity is imparted to said medium by the production of antibiotic 1745A/X and the recovering the antibiotic 1745A/X so produced from said aqueous medium.
Claim 2
Dependent Claim 71 words
A process for the preparation of antibiotic 1745A/X which comprises cultivating Streptomyces antibiotics ATCC 11891, under submerged aerobic conditions, in an aqueous nutrient medium containing assimilable sources of carbohydrates, nitrogen and inorganic salts, to which has been added erythronolide A oxime as the substrate, until substantial antibiotic activity is imparted to said medium by the production of antibiotic 1745A/X and the recovering the antibiotic 1745A/X so produced from said aqueous medium.

References Cited (Backward Citations)

US2757123A Cited
US3928387A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-11-16 1980-05-17 1980-11-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-11-16 1984-05-17 1984-11-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-11-16 1988-05-17 1988-11-16 $7700.00 Window Closed / Lapsed

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